D-Amino Acid Oxidase (DAAO)

Product Description

D-Amino Acid Oxidase (DAAO)
Catalog number: B2013647
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 U
Molecular Weight or Concentration: 15-20 U/mg protein
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: D-Amino Acid Oxidase
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Jiang H, Zhang H, Jiang X, Wu S. Overexpression of D-amino acid oxidase prevents retinal neurovascular pathologies in diabetic rats Diabetologia. 2021 Mar;64(3):693-706.
2: Kuo CY, Lin CH, Lane HY. Targeting D-Amino_Acid Oxidase (DAAO) for the Treatment of Schizophrenia: Rationale and Current Status of Research CNS Drugs. 2022 Nov;36(11):1143-1153.
3: Correll CU. Current Treatment Options and Emerging Agents for Schizophrenia J Clin Psychiatry. 2020 Apr 14;81(3):MS19053BR3C.
4: Murtas G, Sacchi S, Tedeschi G, Maffioli E, Notomista E, Cafaro V, Abbondi M, Mothet JP, Pollegioni L. Antimicrobial D-amino acid oxidase-derived peptides specify gut microbiota Cell Mol Life Sci. 2021 Apr;78(7):3607-3620.
5: Sharma J, Kulshrestha R, Singh N, Jaggi AS. Dual role of D-amino acid oxidase in experimental pain models Eur J Pharmacol. 2019 Jul 15;855:98-102.
6: Bester E, Petzer A, Petzer JP. Coumarin derivatives as inhibitors of d-amino acid oxidase and monoamine oxidase Bioorg Chem. 2022 Jun;123:105791.
7: Pollegioni L, Sacchi S, Murtas G. Human D-Amino Acid Oxidase: Structure, Function, and Regulation Front Mol Biosci. 2018 Nov 28;5:107.
8: Lin YS, Mao WC, Yao NT, Tsai GE. Pharmacokinetics and Safety of Sodium Benzoate, a d-Amino Acid Oxidase (DAAO) Inhibitor, in Healthy Subjects: A Phase I, Open-label Study Clin Ther. 2022 Oct;44(10):1326-1335.
9: Smith SM, Uslaner JM, Hutson PH. The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors Open Med Chem J. 2010 May 27;4:3-9.
10: Murtas G, Caldinelli L, Cappelletti P, Sacchi S, Pollegioni L. Human d-amino acid oxidase: The inactive G183R variant Biochim Biophys Acta Proteins Proteom. 2018 Jul;1866(7):822-830.

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