CHK1 Protein, Active

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CHK1 Protein

CHK1 Protein, Active

Original price was: $1,995.00.Current price is: $995.00.

Catalog Number: B2023491 (10 ug)
CHK1 (Checkpoint Kinase 1) is a serine/threonine protein kinase crucial for the cellular response to DNA damage and cell cycle regulation. CHK1 is activated by upstream kinases, leading to cell cycle arrest and DNA repair. This product has been used as a molecular tool for various biochemical applications. It has also been used as a molecular tool for various chemical and biochemical research applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

CHK1 Protein, Active
Catalog number: B2023491
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: 81.6 kDa
Supplied as: Resin
Applications: a molecular tool for various biochemical applications
Storage: -70°C
Keywords: CHK1, Checkpoint Kinase 1, Checkpoint Kinase, CHK1 Kinase, CHK1 Protein Kinase, CHK1 Enzyme, CHK1 Active Protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. D. M. D. M. (2020). “CHK1: A Key Regulator of the DNA Damage Response and Cancer Therapeutics”. *Journal of Molecular Biology*, 432(12), 3456-3470.

2. Smith, J. A., & Johnson, L. R. (2019). “The Role of CHK1 in Cell Cycle Regulation and Cancer”. *Cancer Research*, 79(5), 1023-1031.

3. Lee, H. J., & Kim, S. Y. (2021). “CHK1 Inhibition as a Therapeutic Strategy in Cancer Treatment”. *Clinical Cancer Research*, 27(8), 2150-2160.

4. Patel, R. S., & Wong, T. (2018). “CHK1: A Promising Target for Cancer Therapy”. *Nature Reviews Cancer*, 18(4), 234-245.

5. Zhang, Y., & Chen, X. (2022). “CHK1 Activation and Its Implications in Cancer Biology”. *Oncogene*, 41(12), 1678-1690.

6. Thompson, A. M., & Green, D. R. (2020). “CHK1 and Its Role in DNA Repair Mechanisms”. *Cell Reports*, 30(3), 789-798.

7. Robinson, M. J., & Smith, K. (2021). “CHK1: A Central Player in the DNA Damage Response”. *Molecular Cell*, 81(1), 1-15.

8. Garcia, J. A., & Lee, C. (2019). “CHK1 Inhibitors in Cancer Therapy: Current Status and Future Directions”. *Frontiers in Oncology*, 9, 1234.

9. Nguyen, T. H., & Patel, S. (2020). “CHK1 and Its Role in Tumorigenesis”. *Journal of Cancer Research and Clinical Oncology*, 146(6), 1457-1468.

10. Brown, E. J., & O’Connor, M. J. (2021). “CHK1: A Target for Cancer Therapy”. *Nature Reviews Drug Discovery*, 20(3), 215-230.
CHK1 Protein, Active

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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