Casein Kinase 2 Phosphorylation Substrate


Catalog Number: B2011066 (1 mg)

Casein Kinase 2 Phosphorylation Substrate is a highly pure peptide containing the consensus phosphorylation sequence for Casein Kinase 2 (CK2, alpha-subunit, sequence RRRDDDSDDD). This product has been used as molecular tool for various chemical, biochemical and immunological applications. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Casein Kinase 2 Phosphorylation Substrate

Catalog number: B2011066
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1264.3 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: -20 °C
Keywords: CK2 substrate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Venerando A, Ruzzene M, Pinna LA. Casein kinase: the triple meaning of a misnomer Biochem J. 2014 Jun 1;460(2):141-56.
2: Suhas KS, Parida S, Gokul C, Srivastava V, Prakash E, Chauhan S, Singh TU, Panigrahi M, Telang AG, Mishra SK. Casein kinase 2 inhibition impairs spontaneous and oxytocin-induced contractions in late pregnant mouse uterus Exp Physiol. 2018 May 1;103(5):621-628.
3: Hitz E, Grüninger O, Passecker A, Wyss M, Scheurer C, Wittlin S, Beck HP, Brancucci NMB, Voss TS. The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis Commun Biol. 2021 Mar 12;4(1):336.
4: Demulder M, De Veylder L, Loris R. Crystal structure of Arabidopsis thaliana casein kinase 2 α1 Acta Crystallogr F Struct Biol Commun. 2020 Apr 1;76(Pt 4):182-191.
5: Borgo C, D’Amore C, Sarno S, Salvi M, Ruzzene M. Protein kinase CK2: a potential therapeutic target for diverse human diseases Signal Transduct Target Ther. 2021 May 17;6(1):183.
6: Husain K, Williamson TT, Nelson N, Ghansah T. Protein kinase 2 (CK2): a potential regulator of immune cell development and function in cancer Immunol Med. 2021 Sep;44(3):159-174.
7: Moreira-Ramos S, Rojas DA, Montes M, Urbina F, Miralles VJ, Maldonado E. Casein kinase 2 inhibits HomolD-directed transcription by Rrn7 in Schizosaccharomyces pombe FEBS J. 2015 Feb;282(3):491-503.
8: Lin F, Cao SB, Ma XS, Sun HX. Inhibition of casein kinase 2 blocks G(2)/M transition in early embryo mitosis but not in oocyte meiosis in mouse J Reprod Dev. 2017 Jun 21;63(3):319-324.
9: Blanquet PR. Casein kinase 2 as a potentially important enzyme in the nervous system Prog Neurobiol. 2000 Feb;60(3):211-46.
10: Schael S, Nüchel J, Müller S, Petermann P, Kormann J, Pérez-Otaño I, Martínez SM, Paulsson M, Plomann M. Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation J Biol Chem. 2013 Mar 29;288(13):9303-12.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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