Cancer Antigen 15-3


Catalog Number: B2012262 (1 kU)
Cancer Antigen 15-3 is a high quality Cancer Antigen 15-3 purified from Human Ascites Fluid. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Cancer Antigen 15-3
Catalog number: B2012262
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 kU
Molecular Weight or Concentration: 5,000 IU/mL
Supplied as: Liquid
Applications: molecular tool for various biochemical applications
Storage: -20C
Keywords: CA 15-3, Tumor Marker 15-3, Mucin-1, MUC-1, Breast carcinoma-associated antigen DF3, Breast Tumor Antigen
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Goodwin PJ, Dowling RJO, Ennis M, Chen BE, Parulekar WR, Shepherd LE, Gelmon KA, Whelan TJ, Ligibel JA, Hershman DL, Mayer IA, Hobday TJ, Rastogi P, Rabaglio-Poretti M, Lemieux J, Thompson AM, Rea DW, Stambolic V. Cancer Antigen 15-3/Mucin 1 Levels in CCTG MA.32: A Breast Cancer Randomized Trial of Metformin vs Placebo JNCI Cancer Spectr. 2021 Jul 28;5(5):pkab066.
2: Li X, Dai D, Chen B, Tang H, Xie X, Wei W. Clinicopathological and Prognostic Significance of Cancer Antigen 15-3 and Carcinoembryonic Antigen in Breast Cancer: A Meta-Analysis including 12,993 Patients Dis Markers. 2018 May 2;2018:9863092.
3: Duffy MJ, Evoy D, McDermott EW. CA 15-3: uses and limitation as a biomarker for breast cancer Clin Chim Acta. 2010 Dec 14;411(23-24):1869-74.
4: Elakkiya V, Menon MP, Nataraj D, Biji P, Selvakumar R. Optical detection of CA 15.3 breast cancer antigen using CdS quantum dot IET Nanobiotechnol. 2017 Apr;11(3):268-276.
5: Hing JX, Mok CW, Tan PT, Sudhakar SS, Seah CM, Lee WP, Tan SM. Clinical utility of tumour marker velocity of cancer antigen 15-3 (CA 15-3) and carcinoembryonic antigen (CEA) in breast cancer surveillance Breast. 2020 Aug;52:95-101.
6: Nath S, Mukherjee P. MUC1: a multifaceted oncoprotein with a key role in cancer progression Trends Mol Med. 2014 Jun;20(6):332-42.
7: Baselice S, Castaldo R, Giannatiempo R, Casaretta G, Franzese M, Salvatore M, Mirabelli P. Impact of Breast Tumor Onset on Blood Count, Carcinoembryonic Antigen, Cancer Antigen 15_3 and Lymphoid Subpopulations Supported by Automatic Classification Approach: A Pilot Study Cancer Control. 2021 Jan-Dec;28:10732748211048612.
8: Haidar S, Bhanushali PB, Shukla KK, Modi D, Puri CP, Badgujar SB, Chugh M. Simplified approach for in-vitro production and purification of cell derived Cancer Antigen 15_3 Int J Biol Macromol. 2018 Feb;107(Pt B):1456-1462.
9: Terävä J, Tiainen L, Lamminmäki U, Kellokumpu-Lehtinen PL, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma PLoS One. 2019 Jul 25;14(7):e0219480.
10: Chen W, Zhang Z, Zhang S, Zhu P, Ko JK, Yung KK. MUC1: Structure, Function, and Clinic Application in Epithelial Cancers Int J Mol Sci. 2021 Jun 18;22(12):6567.

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