Calcein AM (Highly Pure)

Product Description

Calcein AM (Highly Pure)
Catalog number: B2011099
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 994.9 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: -20 °C
Keywords: Calcein-AM, Calcein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Uggeri J, Gatti R, Belletti S, Scandroglio R, Corradini R, Rotoli BM, Orlandini G. Calcein-AM is a detector of intracellular oxidative activity Histochem Cell Biol. 2004 Nov;122(5):499-505.
2: Jonsson B, Liminga G, Csoka K, Fridborg H, Dhar S, Nygren P, Larsson R. Cytotoxic activity of calcein acetoxymethyl ester (Calcein/AM) on primary cultures of human haematological and solid tumours Eur J Cancer. 1996 May;32A(5):883-7.
3: Iwanowicz LR, Densmore CL, Ottinger CA. Calcein AM release-based cytotoxic cell assay for fish leucocytes Fish Shellfish Immunol. 2004 Feb;16(2):127-37.
4: Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells Cancer Cell. 2003 Mar;3(3):285-96.
5: Tawakoli PN, Al-Ahmad A, Hoth-Hannig W, Hannig M, Hannig C. Comparison of different live/dead stainings for detection and quantification of adherent microorganisms in the initial oral biofilm Clin Oral Investig. 2013 Apr;17(3):841-50.
6: Chan LL, McCulley KJ, Kessel SL. Assessment of Cell Viability with Single-, Dual-, and Multi-Staining Methods Using Image Cytometry Methods Mol Biol. 2017;1601:27-41.
7: Tenopoulou M, Kurz T, Doulias PT, Galaris D, Brunk UT. Does the calcein_AM method assay the total cellular ‘labile iron pool’ or only a fraction of it? Biochem J. 2007 Apr 15;403(2):261-6.
8: Lv Y, Liu R, Xie S, Zheng X, Mao J, Cai Y, Chen W. Calcein-acetoxymethy ester enhances the antitumor effects of doxorubicin in nonsmall cell lung cancer by regulating the TopBP1/p53RR pathway Anticancer Drugs. 2017 Sep;28(8):861-868.
9: Bratosin D, Mitrofan L, Palii C, Estaquier J, Montreuil J. Novel fluorescence assay using calcein-AM for the determination of human erythrocyte viability and aging Cytometry A. 2005 Jul;66(1):78-84.
10: Legrand O, Simonin G, Perrot JY, Zittoun R, Marie JP. Both Pgp and MRP1 activities using calcein-AM contribute to drug resistance in AML Adv Exp Med Biol. 1999;457:161-75.

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