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Bis(4-methylumbelliferyl)phosphate (Highly Pure)

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2016490 (100 mg)
Bis(4-methylumbelliferyl)phosphate (Highly Pure) is a high quality Bis(4-methylumbelliferyl)phosphate is a synthetic substrate commonly used in biochemical assays to detect the activity of enzymes such as phosphatases. It is a colorless compound that, when cleaved by the enzyme, releases a fluorescent product that can be easily detected and quantified. This substrate is often used in research and diagnostic laboratories to study enzyme kinetics and to screen for enzyme inhibitors or activators. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

Bis(4-methylumbelliferyl)phosphate (Highly Pure)
Catalog number: B2016490
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: 414.31 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Bis(MU)-phos
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Taylor DG, Williams VM, Crawford N. Bis-(4-methylumbelliferyl) phosphate as a substrate for the surface membrane-associated phosphodiesterase activity of pig platelets Biochim Biophys Acta. 1977 Mar 17;465(3):667-71.
2: Jones CS, Davidson DJ, Callahan JW. Complex kinetics of bis(4-methylumbelliferyl)phosphate and hexadecanoyl(nitrophenyl)phosphorylcholine hydrolysis by purified sphingomyelinase in the presence of Triton X-100 Biochim Biophys Acta. 1982 Mar 4;701(3):261-8.
3: Jones CS, Shankaran P, Callahan JW. Purification of sphingomyelinase to apparent homogeneity by using hydrophobic chromatography Biochem J. 1981 May 1;195(2):373-82.
4: Callahan JW, Jones CS, Davidson DJ, Shankaran P. The active site of lysosomal sphingomyelinase: evidence for the involvement of hydrophobic and ionic groups J Neurosci Res. 1983;10(2):151-63.
5: Levade T, Salvayre R, Douste-Blazy L. Molecular forms of sphingomyelinase and non-specific phosphodiesterases in Epstein-Barr virus-transformed lymphoid cell lines from Niemann-Pick disease types A and B Eur J Biochem. 1985 Jun 3;149(2):405-9.
6: Levade T, Salvayre R, Lenoir G, Douste-Blazy L. Sphingomyelinase and nonspecific phosphodiesterase activities in Epstein-Barr virus-transformed lymphoid cell lines from Niemann-Pick disease A, B and C Biochim Biophys Acta. 1984 Apr 18;793(2):321-4.
7: Yamanaka T, Suzuki K. Acid sphingomyelinase of human brain: purification to homogeneity J Neurochem. 1982 Jun;38(6):1753-64.
8: Besley GT. Diagnosis of Niemann-Pick disease using a simple and sensitive fluorimetric assay of sphingomyelinase activity Clin Chim Acta. 1978 Dec 15;90(3):269-78.
9: Watanabe K, Sakuragawa N, Arima M, Satoyoshi E. Partial purification and properties of acid sphingomyelinase from rat liver J Lipid Res. 1983 May;24(5):596-603.
10: Besley GT, Moss SE. Studies on sphingomyelinase and beta-glucosidase activities in Niemann-Pick disease variants. Phosphodiesterase activities measured with natural and artificial substrates Biochim Biophys Acta. 1983 Jun 16;752(1):54-64.

Products Related to Bis(4-methylumbelliferyl)phosphate (Highly Pure) can be found at Chemicals

Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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