Amyloid β-Protein (Human, 1-42) (Scrambled)

Description

Amyloid β-Protein (Human, 1-42) (Scrambled)
Catalog number: MDP0862
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 4514 g/mol
Supplied as: Trifluoroacetate Salt
Applications: control peptide for the amyloid beta-protein (Human, 1-42)
Storage: -20°C
Keywords: Amyloid beta-Protein (Human, 1-42) (Scrambled), Scrambled beta-Amyloid (1-42); Ala-Ile-Ala-Glu-Gly-Asp-Ser-His-Val-Leu-Lys-Glu-Gly-Ala-Tyr-Met-Glu-Ile-Phe-Asp-Val-Gln-Gly-His-Val-Phe-Gly-Gly-Lys-Ile-Phe-Arg-Val-Val-Asp-Leu-Gly-Ser-His-Asn-Val-Ala
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
Indication for Use:This product is for Research Use Only. This product is NOT for human or animal use.

References:
1: Arbor SC, LaFontaine M, Cumbay M. Amyloid-beta Alzheimer targets – protein
processing, lipid rafts, and amyloid-beta pores. Yale J Biol Med. 2016 Mar
24;89(1):5-21.

2: Mucke L, Selkoe DJ. Neurotoxicity of amyloid β-protein: synaptic and network
dysfunction. Cold Spring Harb Perspect Med. 2012 Jul;2(7):a006338.

3: Gallardo G, Holtzman DM. Amyloid-β and Tau at the Crossroads of Alzheimer’s
Disease. Adv Exp Med Biol. 2019;1184:187-203.

4: Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rowan MJ,
Selkoe DJ. Naturally secreted oligomers of amyloid beta protein potently inhibit
hippocampal long-term potentiation in vivo. Nature. 2002 Apr 4;416(6880):535-9.

5: Selkoe DJ. Alzheimer’s disease is a synaptic failure. Science. 2002 Oct
25;298(5594):789-91.

6: Roher AE, Kokjohn TA, Clarke SG, Sierks MR, Maarouf CL, Serrano GE, Sabbagh
MS, Beach TG. APP/Aβ structural diversity and Alzheimer’s disease pathogenesis.
Neurochem Int. 2017 Nov;110:1-13.

7: Araki W, Tamaoka A. Amyloid beta-protein and lipid rafts: focused on
biogenesis and catabolism. Front Biosci (Landmark Ed). 2015 Jan 1;20:314-24.

8: Kamenetz F, Tomita T, Hsieh H, Seabrook G, Borchelt D, Iwatsubo T, Sisodia S,
Malinow R. APP processing and synaptic function. Neuron. 2003 Mar
27;37(6):925-37.

9: Lei Y, Renyuan Z. Effects of Androgens on the Amyloid-β Protein in
Alzheimer’s Disease. Endocrinology. 2018 Dec 1;159(12):3885-3894.
10: Müller UC, Pietrzik CU, Deller T. The physiological functions of the
β-amyloid precursor protein APP. Exp Brain Res. 2012 Apr;217(3-4):325-9.

Products Related to Amyloid β-Protein (Human, 1-42) (Scrambled): Peptides