Amyloid β-Protein (Human, 1-40)

Product Description

Amyloid β-Protein (Human, 1-40)
Catalog number: MDP0678
CAS Number: 134500-80-4
Sequence: Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Amount: 500 ug
Molecular Weight: 4329.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
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2: Tamano H, Takiguchi M, Shimaya R, Adlard PA, Bush AI, Takeda A. Extracellular Zn(2+)-independently attenuated LTP by human amyloid β(1-40) and rat amyloid β(1-42) Biochem Biophys Res Commun. 2019 Jun 30;514(3):888-892.
3: Illouz T, Madar R, Griffioen K, Okun E. A protocol for quantitative analysis of murine and human amyloid-β(1-40) and (1-42) J Neurosci Methods. 2017 Nov 1;291:28-35.
4: Schimansky A, Yadav JK. Amyloid cross-sequence interaction between Aβ(1-40) and αA(66-80) in relation to the pathogenesis of cataract Int J Biol Macromol. 2021 May 15;179:61-70.
5: Lyons B, Friedrich M, Raftery M, Truscott R. Amyloid Plaque in the Human Brain Can Decompose from Aβ(1-40/1-42) by Spontaneous Nonenzymatic Processes Anal Chem. 2016 Mar 1;88(5):2675-84.
6: Stamatelopoulos K, Pol CJ, Ayers C, Georgiopoulos G, Gatsiou A, Brilakis ES, Khera A, Drosatos K, de Lemos JA, Stellos K. Amyloid-Beta (1-40) Peptide and Subclinical Cardiovascular Disease J Am Coll Cardiol. 2018 Aug 28;72(9):1060-1061.
7: Zhu YJ, Lin H, Lal R. Fresh and nonfibrillar amyloid beta protein(1-40) induces rapid cellular degeneration in aged human fibroblasts: evidence for AbetaP-channel-mediated cellular toxicity FASEB J. 2000 Jun;14(9):1244-54.
8: Poduslo JF, Curran GL, Sanyal B, Selkoe DJ. Receptor-mediated transport of human amyloid beta-protein 1-40 and 1-42 at the blood-brain barrier Neurobiol Dis. 1999 Jun;6(3):190-9.
9: Theda L, Drews MK, Zitnik G, Oshima J, Martin GM. Aβ 1-40 enhances the proliferation of human diploid fibroblasts Neurobiol Aging. 2016 Feb;38:11-13.
10: Maness LM, Banks WA, Podlisny MB, Selkoe DJ, Kastin AJ. Passage of human amyloid beta-protein 1-40 across the murine blood-brain barrier Life Sci. 1994;55(21):1643-50.

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