Name: Ago4 Antibody
Brand: Molecular Depot
SKU: B2016707
Price: 695 USD
Availability: InStock
Rating: 5 (1 reviews)

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Ago4 Antibody

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2016707 (10 µg)
Ago4 Antibody is a high quality protein that is used in scientific research to study gene regulation and RNA interference pathways. It is commonly used to investigate the role of Ago4 protein in various cellular processes, such as gene silencing and post-transcriptional regulation. Researchers use the Ago4 antibody to detect and analyze the expression and localization of Ago4 protein in cells and tissues, providing valuable insights into its function and interactions with other molecules. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

Live enquiry about this product via Text/SMS: 1-858-900-3210.

In stock

SKU: B2016707 Categories: Antibodies, Cell Biology Tag: MD 1000

Product Description

5/5 - (1 vote)

Ago4 Antibody
Catalog number: B2016707
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 µg
Molecular Weight or Concentration: 100 kDa
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: EIF2C4
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Wang L, Li D, Su X, Zhao Y, Huang A, Li H, Li J, Xia W, Jia T, Zhang H, Dong J, Liu X, Shao N. AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner Oncogene. 2023 Jan;42(1):62-77.
2: Wang L, Lozano-Duran R. Arabidopsis AGO4 loses its Cajal body localization when heterologously expressed in Nicotiana benthamiana Commun Integr Biol. 2022 Mar 24;15(1):88-91.
3: Wang F, Axtell MJ. AGO4 is specifically required for heterochromatic siRNA accumulation at Pol V-dependent loci in Arabidopsis thaliana Plant J. 2017 Apr;90(1):37-47.
4: Brosseau C, El Oirdi M, Adurogbangba A, Ma X, Moffett P. Antiviral Defense Involves AGO4 in an Arabidopsis-Potexvirus Interaction Mol Plant Microbe Interact. 2016 Nov;29(11):878-888.
5: Wang F, Huang HY, Huang J, Singh J, Pikaard CS. Enzymatic reactions of AGO4 in RNA-directed DNA methylation: siRNA duplex loading, passenger strand elimination, target RNA slicing, and sliced target retention Genes Dev. 2023 Feb 1;37(3-4):103-118.
6: Miloro F, Kis A, Havelda Z, Dalmadi Á. Barley AGO4 proteins show overlapping functionality with distinct small RNA-binding properties in heterologous complementation Plant Cell Rep. 2024 Mar 13;43(4):96.
7: Modzelewski AJ, Holmes RJ, Hilz S, Grimson A, Cohen PE. AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germline Dev Cell. 2012 Aug 14;23(2):251-64.
8: Nakanishi K. Anatomy of four human Argonaute proteins Nucleic Acids Res. 2022 Jul 8;50(12):6618-6638.
9: Hauptmann J, Kater L, Löffler P, Merkl R, Meister G. Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage RNA. 2014 Oct;20(10):1532-8.
10: Duan CG, Zhang H, Tang K, Zhu X, Qian W, Hou YJ, Wang B, Lang Z, Zhao Y, Wang X, Wang P, Zhou J, Liang G, Liu N, Wang C, Zhu JK. Specific but interdependent functions for Arabidopsis AGO4 and AGO6 in RNA-directed DNA methylation EMBO J. 2015 Mar 4;34(5):581-92.

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