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Acriflavine Conjugated to Biotin

$2,695.00

Catalog Number: B2012438 (1 mg)
Acriflavine Conjugated to Biotin is a high quality conjugate of Acriflavine and Biotin for Research Use Only. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Description

Acriflavine Conjugated to Biotin
Catalog number: B2012438
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 493.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: 3,6-Bis(amino)-9-(biotinylamidoethylamino)acridine, Acriflavine-Biotin, Biotin-Acriflavine
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Sabolova D, Kristian P, Kozurkova M. Proflavine/acriflavine derivatives with versatile biological activities J Appl Toxicol. 2020 Jan;40(1):64-71.
2: Nehme R, Hallal R, El Dor M, Kobeissy F, Gouilleux F, Mazurier F, Zibara K. Repurposing of Acriflavine to Target Chronic Myeloid Leukemia Treatment Curr Med Chem. 2021;28(11):2218-2233.
3: Piorecka K, Kurjata J, Stanczyk WA. Acriflavine, an Acridine Derivative for Biomedical Application: Current State of the Art J Med Chem. 2022 Sep 8;65(17):11415-11432.
4: Hallal R, Nehme R, Brachet-Botineau M, Nehme A, Dakik H, Deynoux M, Dello Sbarba P, Levern Y, Zibara K, Gouilleux F, Mazurier F. Acriflavine targets oncogenic STAT5 signaling in myeloid leukemia cells J Cell Mol Med. 2020 Sep;24(17):10052-10062.
5: Vandghanooni S, Rasoulian F, Eskandani M, Akbari Nakhjavani S, Eskandani M. Acriflavine-loaded solid lipid nanoparticles: preparation, physicochemical characterization, and anti-proliferative properties Pharm Dev Technol. 2021 Nov;26(9):934-942.
6: Kostjukov V. Acriflavine in aqueous solution: excitation and hydration J Mol Model. 2022 Jun 20;28(7):194.
7: Napolitano V, Dabrowska A, Schorpp K, Mourão A, Barreto-Duran E, Benedyk M, Botwina P, Brandner S, Bostock M, Chykunova Y, Czarna A, Dubin G, Fröhlich T, Hölscher M, Jedrysik M, Matsuda A, Owczarek K, Pachota M, Plettenburg O, Potempa J, Rothenaigner I, Schlauderer F, Slysz K, Szczepanski A, Greve-Isdahl Mohn K, Blomberg B, Sattler M, Hadian K, Popowicz GM, Pyrc K. Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses Cell Chem Biol. 2022 May 19;29(5):774-784.e8.
8: Usha G, Prakash R, Karpagalakshmi K, Ramalakshmi S, Piramuthu L, Yang C, Selvapalam N. Supramolecular Assembly of Acriflavine on Graphene Oxide for the Sensing of Adenosine Phosphates Anal Sci. 2020 Nov 10;36(11):1365-1369.
9: Liang J, Zheng M, Xu W, Chen Y, Tang P, Wu G, Zou P, Li H, Chen L. Acriflavine and proflavine hemisulfate as potential antivirals by targeting Mpro Bioorg Chem. 2022 Dec;129:106185.
10: Lian G, Li X, Zhang L, Zhang Y, Sun L, Zhang X, Liu H, Pang Y, Kong W, Zhang T, Wang X, Jiang C. Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway(✰) EBioMedicine. 2019 Nov;49:291-304.

Products Related to Acriflavine Conjugated to Biotin can be found at Conjugates

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