Acetylcholinesterase from Electrophorus electricus (electric eel)

Product Description

Acetylcholinesterase from Electrophorus electricus (electric eel)
Catalog number: B2016631
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 units
Molecular Weight or Concentration: 280 kDa
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: AChE, Acetylcholine acetylhydrolase, Cholinesterase, Acetyl
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Yılmaz C, Khorsheed WM, Babat CF. In vitro and in silico evaluation of inhibitory effects of bisphenol derivatives on acetylcholinesterase of electric eel (Electrophorus electricus L.) Comp Biochem Physiol C Toxicol Pharmacol. 2022 Oct;260:109416.
2: Stasiuk M, Janiszewska A, Kozubek A. Phenolic lipids affect the activity and conformation of acetylcholinesterase from Electrophorus electricus (Electric eel) Nutrients. 2014 Apr 30;6(5):1823-31.
3: Ganeshpurkar A, Singh R, Shivhare S, Divya, Kumar D, Gutti G, Singh R, Kumar A, Singh SK. Improved machine learning scoring functions for identification of Electrophorus electricus’s acetylcholinesterase inhibitors Mol Divers. 2022 Jun;26(3):1455-1479.
4: Kasteel EEJ, Nijmeijer SM, Darney K, Lautz LS, Dorne JLCM, Kramer NI, Westerink RHS. Acetylcholinesterase inhibition in electric eel and human donor blood: an in vitro approach to investigate interspecies differences and human variability in toxicodynamics Arch Toxicol. 2020 Dec;94(12):4055-4065.
5: Musset F, Frobert Y, Grassi J, Vigny M, Boulla G, Bon S, Massoulié J. Monoclonal antibodies against acetylcholinesterase from electric organs of Electrophorus and Torpedo Biochimie. 1987 Feb;69(2):147-56.
6: Nunes-Tavares N, Nery da Matta A, Batista e Silva CM, Araújo GM, Louro SR, Hassón-Voloch A. Inhibition of acetylcholinesterase from Electrophorus electricus (L.) by tricyclic antidepressants Int J Biochem Cell Biol. 2002 Sep;34(9):1071-9.
7: Forsberg A, Puu G. Kinetics for the inhibition of acetylcholinesterase from the electric eel by some organophosphates and carbamates Eur J Biochem. 1984 Apr 2;140(1):153-6.
8: López MD, Campoy FJ, Pascual-Villalobos MJ, Muñoz-Delgado E, Vidal CJ. Acetylcholinesterase activity of electric eel is increased or decreased by selected monoterpenoids and phenylpropanoids in a concentration-dependent manner Chem Biol Interact. 2015 Mar 5;229:36-43.
9: Sikorav JL, Grassi J, Bon S. Synthesis in vitro of precursors of the catalytic subunits of acetylcholinesterase from Torpedo marmorata and Electrophorus electricus Eur J Biochem. 1984 Dec 17;145(3):519-24.
10: Silman I, Anglister L. Electric eel acetylcholinesterase: a multisubunit enzyme containing a collagen tail Monogr Neural Sci. 1980;7:55-69.

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