Acetyl-Calpastatin (184-210) (Human)

Product Description

Acetyl-Calpastatin (184-210) (Human)
Catalog number: B2019116
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: N/A
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: Calpastatin|123714-50-1|Calpastatin Peptide B27-WT|AC-ASP-PRO-MET-SER-SER-THR-TYR-ILE-GLU-GLU-LEU-GLY-LYS-ARG-GLU-VAL-THR-ILE-PRO-PRO-LYS-TYR-ARG-GLU-L|acetyl-calpastatin (184-210)|CHEBI:131884|calpastatin peptide Ac 184-210|Ac-calpastatin(184-210)(human)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Squier MK, Sehnert AJ, Sellins KS, Malkinson AM, Takano E, Cohen JJ. Calpain and calpastatin regulate neutrophil apoptosis J Cell Physiol. 1999 Mar;178(3):311-9.
3: Peintner L, Venkatraman A, Waeldin A, Hofherr A, Busch T, Voronov A, Viau A, Kuehn EW, Köttgen M, Borner C. Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner Autophagy. 2021 Sep;17(9):2384-2400.
4: Kato M, Nonaka T, Maki M, Kikuchi H, Imajoh-Ohmi S. Caspases cleave the amino-terminal calpain inhibitory unit of calpastatin during apoptosis in human Jurkat T cells J Biochem. 2000 Feb;127(2):297-305.
5: Seo J, Jo SA, Hwang S, Byun CJ, Lee HJ, Cho DH, Kim D, Koh YH, Jo I. Trichostatin A epigenetically increases calpastatin expression and inhibits calpain activity and calcium-induced SH-SY5Y neuronal cell toxicity FEBS J. 2013 Dec;280(24):6691-701.
6: Gil-Parrado S, Assfalg-Machleidt I, Fiorino F, Deluca D, Pfeiler D, Schaschke N, Moroder L, Machleidt W. Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: enhancing cell permeability by conjugation with penetratin Biol Chem. 2003 Mar;384(3):395-402.
7: Yang H, Murthy S, Sarkar FH, Sheng S, Reddy GP, Dou QP. Calpain-mediated androgen receptor breakdown in apoptotic prostate cancer cells J Cell Physiol. 2008 Dec;217(3):569-76.
8: Gil-Parrado S, Fernández-Montalván A, Assfalg-Machleidt I, Popp O, Bestvater F, Holloschi A, Knoch TA, Auerswald EA, Welsh K, Reed JC, Fritz H, Fuentes-Prior P, Spiess E, Salvesen GS, Machleidt W. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members J Biol Chem. 2002 Jul 26;277(30):27217-26.
9: Kim H, Zamel R, Bai XH, Lu C, Keshavjee S, Keshavjee S, Liu M. Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L595-L608.
https://pubmed.ncbi.nlm.nih.gov/11312270

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