α-Endorphin

Product Description

α-Endorphin
Catalog number: MDP0404
CAS Number: 64190-70-1
Sequence: Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr
Amount: 500 ug
Molecular Weight: 1745.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: He X, Huang L, Qiu S, Yin X, Shen Y, Wu Y, Jiang Y, Fang J. β-Endorphin attenuates collagen-induced arthritis partially by inhibiting peripheral pro-inflammatory mediators Exp Ther Med. 2018 Apr;15(4):4014-4018.
2: Garzón-Niño J, Cortés-Montero E, Rodríguez-Muñoz M, Sánchez-Blázquez P. (α)N-Acetyl β-Endorphin Is an Endogenous Ligand of σ1Rs That Regulates Mu-Opioid Receptor Signaling by Exchanging G Proteins for σ2Rs in σ1R Oligomers Int J Mol Sci. 2022 Dec 29;24(1):582.
3: De Wied D, Van Ree JM. Non-opiate effects of neuropeptides derived from beta-endorphin Pol J Pharmacol Pharm. 1987 Sep-Oct;39(5):623-32.
4: Gilman SC, Schwartz JM, Milner RJ, Bloom FE, Feldman JD. beta-Endorphin enhances lymphocyte proliferative responses Proc Natl Acad Sci U S A. 1982 Jul;79(13):4226-30.
5: Reed B, Bidlack JM, Chait BT, Kreek MJ. Extracellular biotransformation of beta-endorphin in rat striatum and cerebrospinal fluid J Neuroendocrinol. 2008 May;20(5):606-16.
6: Wu HY, Tang XQ, Mao XF, Wang YX. Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression J Neurosci. 2017 Nov 29;37(48):11701-11714.
7: Dores RM, Steveson TC, Price ML. A view of the N-acetylation of alpha-melanocyte-stimulating hormone and beta-endorphin from a phylogenetic perspective Ann N Y Acad Sci. 1993 May 31;680:161-74.
8: Tanaka K. [Corticotrope] Nihon Rinsho. 1993 Oct;51(10):2606-10.
9: Davis TP, Culling AJ, Schoemaker H, Galligan JJ. beta-Endorphin and its metabolites stimulate motility of the dog small intestine J Pharmacol Exp Ther. 1983 Nov;227(2):499-507.
10: Duque E, Mangas A, Salinas P, Díaz-Cabiale Z, Narváez JA, Coveñas R. Mapping of alpha-neo-endorphin- and neurokinin B-immunoreactivity in the human brainstem Brain Struct Funct. 2013 Jan;218(1):131-49.

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