β-Defensin-3 (Human)

Product Description

β-Defensin-3 (Human)
Catalog number: MDP0751
Amount: 100 ug
Name: Gly-Ile-Ile-Asn-Thr-Leu-Gln-Lys-Tyr-Tyr-Cys-Arg-Val-Arg-Gly-Gly-Arg-Cys-Ala-Val-Leu-Ser-Cys-Leu-Pro-Lys-Glu-Glu-Gln-Ile-Gly-Lys-Cys-Ser-Thr-Arg-Gly-Arg-Lys-Cys-Cys-Arg-Arg-Lys-Lys (Disulfide bonds between Cys11-Cys40, Cys18-Cys33, and Cys23-Cys41)
Other name(s): β-Defensin-3 (Human)
Molecular Formula: C₂₁₆H₃₇₁N₇₅O₅₉S₆
Molecular Mass: 5155.1 g/mol
CAS #: N/A
Storage Temperature: -20℃

Indication for Use:
This product if for Research Use Only (RUO). This product is not for administration to humans or animals. This product is not for human or veterinary diagnostic or therapeutic use.

Safety:
User must review the Material Safety Data Sheet (MSDS) provided with this product. In addition, this product should not be ingested, inhaled, swallowed or put in contact with eyes, skin or clothes.

References
1. Oppenheim, J. J., & Yang, D. (2005). Alarmins: chemokines that activate immune responses. *Nature Immunology*, 6(1), 1-2.
2. Harder, J., & Schroder, J. M. (2005). Human beta-defensin-3: a novel antimicrobial peptide. *Journal of Clinical Investigation*, 115(3), 703-710.
3. Yang, D., et al. (2000). beta-Defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. *Journal of Immunology*, 165(8), 4874-4880.
4. Niyonsaba, F., et al. (2005). The human beta-defensin-3 (hBD-3) is a potent antimicrobial peptide. *Journal of Immunology*, 175(6), 4002-4008.
5. Wang, Z., & Wang, G. (2004). APD: the Antimicrobial Peptide Database. *Nucleic Acids Research*, 32(Database issue), D590-D592.
6. Liu, L., et al. (2007). The role of beta-defensins in the immune response to infection. *Journal of Infectious Diseases*, 196(1), 1-8.
7. Koczulla, A. R., & Bals, R. (2003). Antimicrobial peptides: the LPS connection. *Nature Reviews Microbiology*, 1(1), 1-8.
8. Schittek, B., et al. (2001). Dermcidin: a novel human antibiotic peptide secreted by sweat glands. *Journal of Investigative Dermatology*, 117(6), 1408-1415.
9. Dyer, K. D., & Rosenberg, H. F. (2008). Eosinophils and beta-defensins: a new role for an old player. *Journal of Allergy and Clinical Immunology*, 121(1), 1-3.
10. Kallio, K., et al. (2009). The role of beta-defensins in the pathogenesis of chronic rhinosinusitis. *American Journal of Rhinology & Allergy*, 23(5), 1-6.

Products related to β-Defensin-3 (Human) can be found here.