Catalog Number: MDP0135 (1 mg)
7-Amino-4-methylcoumarin is a high quality 7-Amino-4-methylcoumarin. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: MDP0135 Categories: , Tag:


Catalog number: MDP0135
CAS Number: 348086-66-8
Sequence: 7-Amino-4-methylcoumarin
Amount: 1 mg
Molecular Weight: 174.8 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

1: Liu Y, Liu X, Zhang N, Yin M, Dong J, Zeng Q, Mao G, Song D, Liu L, Deng H. Berberine diminishes cancer cell PD-L1 expression and facilitates antitumor immunity via inhibiting the deubiquitination activity of CSN5 Acta Pharm Sin B. 2020 Dec;10(12):2299-2312.
2: Takase H, Murase T, Hachisuka D, Sakamoto Y, Sugiura M, Nakano S, Fujii K, Masaki A, Inagaki H. 7-Amino-4-methylcoumarin as a fluorescent substitute for Schiff’s reagent: a new method that can be combined with hemalum and eosin staining on the same tissue section Biotech Histochem. 2023 Jan;98(1):54-61.
3: Żamojć K, Wiczk W, Zaborowski B, Jacewicz D, Chmurzyński L. Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt C:1875-80.
4: Sun X, Guo Y, Wen R, Li H. A highly sensitive and selective ratiometric sensing platform based on 7-amino-4-methylcoumarin for naked-eye visual fluorescence sensing of Cu(2) Spectrochim Acta A Mol Biomol Spectrosc. 2022 Feb 15;267(Pt 2):120627.
5: Sun X, Li J, He Q, Xue Y, Bai Y, Yang Y, Wang X, Wang S, Li R. Ferric ion detection mechanism of a dicarboxylic cellulose nanocrystal and a 7-amino-4-methylcoumarin based fluorescent chemosensor RSC Adv. 2022 Jun 7;12(26):16798-16804.
6: Tandon R, Ponnan P, Aggarwal N, Pathak R, Baghel AS, Gupta G, Arya A, Nath M, Parmar VS, Raj HG, Prasad AK, Bose M. Characterization of 7-amino-4-methylcoumarin as an effective antitubercular agent: structure-activity relationships J Antimicrob Chemother. 2011 Nov;66(11):2543-55.
7: Aubry JP, Durand I, De Paoli P, Banchereau J. 7-amino-4-methylcoumarin-3-acetic acid-conjugated streptavidin permits simultaneous flow cytometry analysis of either three cell surface antigens or one cell surface antigen as a function of RNA and DNA content J Immunol Methods. 1990 Mar 27;128(1):39-49.
8: Molina-Bolívar JA, Galisteo-González F, Ruiz CC, Medina-O’Donnell M, Martínez A, Parra A. Maslinic acid conjugate with 7-amino-4-methylcoumarin as probe to monitor the temperature dependent conformational changes of human serum albumin by FRET Spectrochim Acta A Mol Biomol Spectrosc. 2019 May 5;214:161-169.
9: Choi MG, Lee E, Chung HS, Jang SH, Lee C. A fluorogenic method for measuring enteropeptidase activity: spectral shift in the emission of GD4K-conjugated 7-amino-4-methylcoumarin BMB Rep. 2011 Jul;44(7):458-61.
10: Yamamoto S, Nagai E, Asada Y, Kinoshita M, Suzuki S. A rapid and highly sensitive microchip electrophoresis of mono- and mucin-type oligosaccharides labeled with 7-amino-4-methylcoumarin Anal Bioanal Chem. 2015 Feb;407(5):1499-503.

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