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5-Fluorouracil (Ultra High Purity ≥ 99%)

$395.00

Catalog Number: B2010420 (1 g)
5-Fluorouracil (Ultra High Purity ≥ 99%) is a high quality research product used as Ultra high purity 5-Fluorouracil (≥99% by HPLC). This compound has been used in research experiments involving the induction of apoptosis. Custom bulk orders of this product are available upon request.
Live Enquiry about this product via Text/SMS: 1-858-900-3210.

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SKU: B2010420 Categories: , ,

Description

5-Fluorouracil (Ultra High Purity ≥ 99%)
Catalog number: B2010420
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 g
Molecular Weight or Concentration: 130.08
Supplied as: Powder
Appearance: White Powder
Applications: Ultra high purity 5-Fluorouracil (≥99% by HPLC). This compound has been used in research experiments involving the induction of apoptosis.
Storage: RT
Keywords: 5-Fluoro-2,4(1H,3H)-pyrimidinedione, 2,4-Dihydroxy-5-fluoropyrimidine, 5-FU
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Hashimoto Y, Yoshida Y, Yamada T, Aisu N, Yoshimatsu G, Yoshimura F, Hasegawa
S. Current Status of Therapeutic Drug Monitoring of 5-Fluorouracil Prodrugs.
Anticancer Res. 2020 Aug;40(8):4655-4661.

2: Kobuchi S, Ito Y. Application of Pharmacometrics of 5-Fluorouracil to
Personalized Medicine: A Tool for Predicting Pharmacokinetic-
Pharmacodynamic/Toxicodynamic Responses. Anticancer Res. 2020
Dec;40(12):6585-6597.

3: Šuleková M, Váhovská L, Hudák A, Žid L, Zeleňák V. A Study of 5-Fluorouracil
Desorption from Mesoporous Silica by RP-UHPLC. Molecules. 2019 Apr 3;24(7):1317.

4: Freeman NJ, Costanza ME. 5-Fluorouracil-associated cardiotoxicity. Cancer.
1988 Jan 1;61(1):36-45.

5: Pan X, Wang C, Wang F, Li P, Hu Z, Shan Y, Zhang J. Development of
5_Fluorouracil derivatives as anticancer agents. Curr Med Chem.
2011;18(29):4538-56.

6: Thomas DM, Zalcberg JR. 5_fluorouracil: a pharmacological paradigm in the use
of cytotoxics. Clin Exp Pharmacol Physiol. 1998 Nov;25(11):887-95.

7: Bostelman C. 5-Fluorouracil Infiltrations and Ambulatory Pumps: Education,
Prevention, and Management Considerations. Clin J Oncol Nurs. 2019 Oct
1;23(5):537-539.

8: Ilem-Ozdemir D, Atlihan-Gundogdu E, Ekinci M, Halay E, Ay K, Karayildirim T,
Asikoglu M. Radiolabeling and in vitro evaluation of a new 5_fluorouracil
derivative with cell culture studies. J Labelled Comp Radiopharm. 2019
Nov;62(13):874-884.

9: Deng R, Shi L, Zhu W, Wang M, Guan X, Yang D, Shen B. Pharmacokinetics-based
Dose Management of 5-Fluorouracil Clinical Research in Advanced Colorectal
Cancer Treatment. Mini Rev Med Chem. 2020;20(2):161-167.

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