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5-Chloroindole (Highly Pure)

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2016295 (10 g)
5-Chloroindole (Highly Pure) is a high quality compound useful in the synthesis of 5-chloro-tryptamine. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

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5-Chloroindole (Highly Pure)
Catalog number: B2016295
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 g
Molecular Weight or Concentration: 151.60 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: 5-Chloroindole
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Newman AS, Batis N, Grafton G, Caputo F, Brady CA, Lambert JJ, Peters JA, Gordon J, Brain KL, Powell AD, Barnes NM. 5-Chloroindole: a potent allosteric modulator of the 5-HT₃ receptor Br J Pharmacol. 2013 Jul;169(6):1228-38.
2: Jensen JB, Egsgaard H, Van Onckelen H, Jochimsen BU. Catabolism of indole-3-acetic acid and 4- and 5-chloroindole-3-acetic acid in Bradyrhizobium japonicum J Bacteriol. 1995 Oct;177(20):5762-6.
3: Price KL, Lummis SCR. Characterization of a 5-HT(3)-ELIC Chimera Revealing the Sites of Action of Modulators ACS Chem Neurosci. 2018 Jun 20;9(6):1409-1415.
4: Youssif BGM, Mohamed AM, Osman EEA, Abou-Ghadir OF, Elnaggar DH, Abdelrahman MH, Treamblu L, Gomaa HAM. 5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents Eur J Med Chem. 2019 Sep 1;177:1-11.
5: Kholodar SA, Lang G, Cortopassi WA, Iizuka Y, Brah HS, Jacobson MP, England PM. Analogs of the Dopamine Metabolite 5,6-Dihydroxyindole Bind Directly to and Activate the Nuclear Receptor Nurr1 ACS Chem Biol. 2021 Jul 16;16(7):1159-1163.
6: Sural S, Botero JQ, Hobert O, Tekle-Smith M. Protocol to synthesize the auxin analog 5-Ph-IAA for conditional protein depletion in C. elegans using the AID2 system STAR Protoc. 2024 Mar 15;5(1):102901.
7: Boya BR, Lee JH, Lee J. Antibiofilm and Antimicrobial Activities of Chloroindoles Against Uropathogenic Escherichia coli Front Microbiol. 2022 Jun 16;13:872943.
8: Yan Z, Li S, Wang Y, Li J, Ma C, Guo Y, Zhang L. Discovery of novel heterocyclic derivatives as potential glycogen phosphorylase inhibitors with a cardioprotective effect Bioorg Chem. 2022 Dec;129:106120.
9: Xu L, Sun H. Pharmacological manipulation of brain glycogenolysis as a therapeutic approach to cerebral ischemia Mini Rev Med Chem. 2010 Oct;10(12):1188-93.
10: Ahmed M, Briggs MA, Bromidge SM, Buck T, Campbell L, Deeks NJ, Garner A, Gordon L, Hamprecht DW, Holland V, Johnson CN, Medhurst AD, Mitchell DJ, Moss SF, Powles J, Seal JT, Stean TO, Stemp G, Thompson M, Trail B, Upton N, Winborn K, Witty DR. Bicyclic heteroarylpiperazines as selective brain penetrant 5-HT6 receptor antagonists Bioorg Med Chem Lett. 2005 Nov 1;15(21):4867-71.

Products Related to 5-Chloroindole (Highly Pure) can be found at Chemicals

Additional Information

Weight 2.6 oz
Dimensions 3.3 × 1.2 × 1.2 in
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