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5-bromo-6-chloro-3-indoxyl-2-acetamido-2-deoxy-β-D-glucopyranoside

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2015489 (50 mg)
5-bromo-6-chloro-3-indoxyl-2-acetamido-2-deoxy-β-D-glucopyranoside is a high quality chromogenic substrate for N-Acetyl-β-D-glucosaminidase and yields a magenta precipitate. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

5-bromo-6-chloro-3-indoxyl-2-acetamido-2-deoxy-β-D-glucopyranoside
Catalog number: B2015489
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 449.69 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: Magenta-β-D-GlcNAc
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Hu X, Zhang W, Oliver AG, Serianni AS. Methyl 2-acetamido-2-deoxy-β-D-glucopyranoside dihydrate and methyl 2-formamido-2-deoxy-β-D-glucopyranoside Acta Crystallogr C. 2011 Apr;67(Pt 4):o146-50.
2: Chow P, Weissmann B. 4-Methylumbelliferyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, a fluorogenic substrate for N-acetyl-alpha-D-glucosaminidase Carbohydr Res. 1981 Oct 1;96(1):87-93.
3: Sato T, Takashiba M, Hayashi R, Zhu X, Yamagata T. Glycosylation of dodecyl 2-acetamido-2-deoxy-beta-D-glucopyranoside and dodecyl beta-D-galactopyranosyl-(1–>4)-2-acetamido-2-deoxy-beta-D-glucopyranoside as saccharide primers in cells Carbohydr Res. 2008 Apr 7;343(5):831-8.
4: Cai Y, Ling CC, Bundle DR. Concise and efficient synthesis of 2-acetamido-2-deoxy-beta-D-hexopyranosides of diverse aminosugars from 2-acetamido-2-deoxy-beta-D-glucose J Org Chem. 2009 Jan 16;74(2):580-9.
5: Ballardie FW, Capon B, Dearie WM, Foster RL. Neighbouring acetamido-group participation in reactions of derivatives of 2-acetamido-2-deoxy-D-glucose Carbohydr Res. 1976 Jul;49:79-92.
6: Zhang J, Chen H, Kornreich R, Yu C. Prenatal Diagnosis of Tay-Sachs Disease Methods Mol Biol. 2019;1885:233-250.
7: Allen AK, Davies RC, Neuberger A. The separation of methyl ethers of methyl 2-acetamido-2-deoxy-D-glucopyranosides on a strongly basic ion-exchange resin Carbohydr Res. 1976 Nov;51(2):149-55.
8: Rabuka D, Hindsgaul O. Synthesis and NMR characterization of the six regioisomeric monophosphates of octyl beta-D-galactopyranosyl-(1 –> 4)-2-acetamido-2-deoxy-beta-D-glucopyranoside Carbohydr Res. 2002 Nov 19;337(21-23):2127-51.
9: Kapešová J, Petrásková L, Kulik N, Straková Z, Bojarová P, Markošová K, Rebroš M, Křen V, Slámová K. Transglycosidase activity of glycosynthase-type mutants of a fungal GH20 β-N-acetylhexosaminidase Int J Biol Macromol. 2020 Oct 15;161:1206-1215.
10: Huang GL, Zhang DW, Zhao HJ, Zhang HC, Wang PG. Chemo-enzymatic synthesis of allyl penta-N-acetyl-chitopentaose Bioorg Med Chem Lett. 2006 Apr 1;16(7):2042-3.

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Additional Information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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