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4-Thiouracil (Highly Pure)

$395.00

Catalog Number: B2013159 (50 mg)
4-Thiouracil (Highly Pure) is a high quality photoactivatable probe to detect nucleic acids structures. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2013159 Categories: , Tag:

Description

4-Thiouracil (Highly Pure)
Catalog number: B2013159
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 128.1 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: 2-hydroxy-4-Mercaptopyrimidine, 4-Thiopyrimidin-2-one, 4-TU
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Zhou J, Pecqueur L, Aučynaitė A, Fuchs J, Rutkienė R, Vaitekūnas J, Meškys R, Boll M, Fontecave M, Urbonavičius J, Golinelli-Pimpaneau B. Structural Evidence for a [4Fe-5S] Intermediate in the Non-Redox Desulfuration of Thiouracil Angew Chem Int Ed Engl. 2021 Jan 4;60(1):424-431.
2: Braun C, Knüppel R, Perez-Fernandez J, Ferreira-Cerca S. Non-radioactive In Vivo Labeling of RNA with 4-Thiouracil Methods Mol Biol. 2022;2533:199-213.
3: Ruckenbauer M, Mai S, Marquetand P, González L. Photoelectron spectra of 2-thiouracil, 4-thiouracil, and 2,4-dithiouracil J Chem Phys. 2016 Feb 21;144(7):074303.
4: Liu T, Han C, Fang P, Ma Z, Wang X, Chen H, Wang S, Meng F, Wang C, Zhang E, Dong G, Zhu H, Yin W, Wang J, Zuo X, Qiu M, Wang J, Qian X, Shen H, Xu L, Hu Z, Yin R. Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma J Hematol Oncol. 2022 Oct 8;15(1):141.
5: Alcolea Palafox M, Franklin Benial AM, K Rastogi V. Biomolecules of 2-Thiouracil, 4-Thiouracil and 2,4-Dithiouracil: A DFT Study of the Hydration, Molecular Docking and Effect in DNA:RNAMicrohelixes Int J Mol Sci. 2019 Jul 15;20(14):3477.
6: Nam Y, Montorsi F, Keefer D, Cavaletto SM, Lee JY, Nenov A, Garavelli M, Mukamel S. Time-Resolved Optical Pump-Resonant X-ray Probe Spectroscopy of 4-Thiouracil: A Simulation Study J Chem Theory Comput. 2022 May 10;18(5):3075-3088.
7: Dolak L, Sokolski WT, Mizsak S, Stroman DW, Sebek OK. Microbial formation of 4-thiouracil Antimicrob Agents Chemother. 1977 Mar;11(3):569-70.
8: Roche KL, Nukui M, Krishna BA, O’Connor CM, Murphy EA. Selective 4-Thiouracil Labeling of RNA Transcripts within Latently Infected Cells after Infection with Human Cytomegalovirus Expressing Functional Uracil Phosphoribosyltransferase J Virol. 2018 Oct 12;92(21):e00880-18.
9: Li X, Chen J, Bowen KH. Photoelectron spectroscopic study of the negative ions of 4-thiouracil and 2,4-dithiouracil J Chem Phys. 2011 Feb 21;134(7):074304.
10: Zou X, Dai X, Liu K, Zhao H, Song D, Su H. Photophysical and photochemical properties of 4-thiouracil: time-resolved IR spectroscopy and DFT studies J Phys Chem B. 2014 Jun 5;118(22):5864-72.

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