4-Aminosalicylic Acid

Product Description

4-Aminosalicylic Acid
Catalog number: B2015796
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 g
Molecular Weight or Concentration: 153.14
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: Dry
Keywords: 4-Amino-2-hydroxybenzoic acid, PAS
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic_acid for inflammatory bowel disease World J Gastroenterol. 2014 Apr 7;20(13):3564-71.
3: Para-aminosalicylic acid Tuberculosis (Edinb). 2008 Mar;88(2):137-8.
4: Borbála Horváth L, Krátký M, Pflégr V, Méhes E, Gyulai G, Kohut G, Babiczky Á, Biri-Kovács B, Baranyai Z, Vinšová J, Bősze S. Host cell targeting of novel antimycobacterial 4-aminosalicylic_acid derivatives with tuftsin carrier peptides Eur J Pharm Biopharm. 2022 May;174:111-130.
5: Grossjohann C, Serrano DR, Paluch KJ, O’Connell P, Vella-Zarb L, Manesiotis P, Mccabe T, Tajber L, Corrigan OI, Healy AM. Polymorphism in sulfadimidine/4-aminosalicylic acid cocrystals: solid-state characterization and physicochemical properties J Pharm Sci. 2015 Apr;104(4):1385-98.
6: Bodart L, Derlet A, Buol X, Leyssens T, Tumanov N, Wouters J. Combining Two Antitubercular Drugs, Clofazimine and 4-Aminosalicylic Acid, in Order to Improve Clofazimine Aqueous Solubility and 4-Aminosalicylic Acid Thermal Stability J Pharm Sci. 2020 Dec;109(12):3645-3652.
7: Drozd KV, Manin AN, Churakov AV, Perlovich GL. Drug-drug cocrystals of antituberculous 4-aminosalicylic acid: Screening, crystal structures, thermochemical and solubility studies Eur J Pharm Sci. 2017 Mar 1;99:228-239.
8: Bouz G, Šlechta P, Jand’ourek O, Konečná K, Paterová P, Bárta P, Novák M, Kučera R, Dal NK, Fenaroli F, Zemanová J, Forbak M, Korduláková J, Pavliš O, Kubíčková P, Doležal M, Zitko J. Hybridization Approach Toward Novel Antituberculars: Design, Synthesis, and Biological Evaluation of Compounds Combining Pyrazinamide and 4-Aminosalicylic Acid ACS Infect Dis. 2023 Jan 13;9(1):79-96.
9: Chejara DR, Mabrouk M, Kumar P, Choonara YE, Kondiah PPD, Badhe RV, Toit LCD, Bijukumar D, Pillay V. Synthesis and Evaluation of a Sodium Alginate-4-Aminosalicylic Acid Based Microporous Hydrogel for Potential Viscosupplementation for Joint Injuries and Arthritis-Induced Conditions Mar Drugs. 2017 Aug 16;15(8):257.
10: Li Y, Liang Y, Fang YY, Chen J, Zheng XW, Zhou WW, Lu LL, Aschner M, Ou SY, Jiang YM. Effects of sodium para-aminosalicylic acid on chelation treatment in Pb-exposed mice Toxicol Ind Health. 2023 Aug;39(8):464-470.

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