3,6-Anhydro-heptakis(6-deoxy-6-(2-carboxyethyl)thio)-gamma-cyclodextrin

Product Description

3,6-Anhydro-heptakis(6-deoxy-6-(2-carboxyethyl)thio)-gamma-cyclodextrin
Catalog number: B2027389
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 mg
Molecular Weight or Concentration: NA
Supplied as: Chemicals
Storage: −80°C
Keywords: Sugammadex Impurity A, Mono-3,6-anhydro sugammadex, 3,6-Anhydro sugammadex

References:
1. Bom, A., Bradley, M., Cameron, K., Clark, J. K., Van Egmond, J., Feilden, H., … & Zhang, M. Q. (2002). A novel concept of reversing neuromuscular block: chemical encapsulation of rocuronium bromide by a cyclodextrin-based synthetic host. Angewandte Chemie International Edition, 41(2), 265-268.
2. Adam, J. M., Bennett, D. J., Bom, A., Clark, J. K., Feilden, H., Hutchinson, E. J., … & Zhang, M. Q. (2002). Cyclodextrin-derived host molecules as reversal agents for the neuromuscular blocker rocuronium bromide. Journal of Medicinal Chemistry, 45(9), 1806-1816.
3. Gijsenbergh, F., Ramael, S., Houwing, N., & van Iersel, T. (2005). First human exposure of Org 25969, a novel agent to reverse the action of rocuronium bromide. Anesthesiology, 103(4), 695-703.
4. Nicholson, W. T., Sprung, J., & Jankowski, C. J. (2007). Sugammadex: a novel agent for the reversal of neuromuscular blockade. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 27(8), 1181-1188.
5. Suy, K., Morias, K., Cammu, G., Hans, P., van Duijnhoven, W. G., Heeringa, M., & Demeyer, I. (2007). Effective reversal of moderate rocuronium- or vecuronium-induced neuromuscular block with sugammadex, a selective relaxant binding agent. Anesthesiology, 106(2), 283-288.
6. Sacan, O., White, P. F., Tufanogullari, B., & Klein, K. (2007). Sugammadex reversal of rocuronium-induced neuromuscular block: a comparison with neostigmine. Anesthesia & Analgesia, 104(3), 569-574.
7. Puhringer, F. K., Gordon, M., Demeyer, I., Sparr, H. J., Ingimarsson, J., Klarin, B., … & van Duijnhoven, W. G. (2008). Sugammadex rapidly reverses moderate rocuronium-or vecuronium-induced neuromuscular block. Anesthesiology, 109(5), 815-822.
8. Antonik, L. J., Goldwater, D. R., Kilford, P. C., Evarts, J. B., & Shi, H. (2009). Sugammadex for reversal of neuromuscular blockade induced by rocuronium in patients with end-stage renal disease. BMC Anesthesiology, 9(1), 5.
9. Abrishami, A., Ho, J., Wong, J., Yin, L., & Chung, F. (2009). Sugammadex, a selective relaxant binding agent, for reversal of neuromuscular blockade: a systematic review and meta-analysis. Anaesthesia, 64(7), 735-743.
10. Welliver, M. (2006). New drug survey: Sugammadex sodium. AANA Journal, 74(5), 357-363.
3,6-Anhydro-heptakis(6-deoxy-6-(2-carboxyethyl)thio)-gamma-cyclodextrin

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