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2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide

Original price was: $795.00.Current price is: $395.00.

Catalog Number: B2027271 (1 g)
2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide is an azido-functionalized derivative of D-glucose widely used as a building block in carbohydrate chemistry and chemical biology. Featuring a protected carbohydrate core with four acetyl groups and an anomeric azide group, it serves as a versatile intermediate for copper(I)-catalyzed azide-alkyne cycloaddition “click chemistry” reactions and the synthesis of N-glycosyl amides and glycoconjugates. Supplied as a high-purity solid reagent, this compound is ideal for glycopeptide synthesis. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (1 vote)

2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide
Catalog number: B2027271
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 g
Molecular Weight or Concentration: 373.32
Supplied as: Powder
Storage: NA
Keywords: 2,3,4,6-Tetra-O-acetyl-beta-D-glucopyranosyl azide, 1-Azido-1-deoxy-beta-D-glucopyranoside tetraacetate, 2,3,4,6-Tetra-O-acetyl-beta-D-glucosyl azide, 1-Azido-2,3,4,6-tetra-O-acetyl-1-deoxy-beta-D-glucopyranose

References:
1. Holden, H. M., Rayment, I., & Thoden, J. B. (2003). Structure and function of enzymes involved in the Leloir pathway for galactose metabolism. Journal of Biological Chemistry, 278(45), 43885-43888.
2. Frey, P. A. (1996). The Leloir pathway: a century of biochemistry and genetics. FASEB Journal, 10(4), 461-470.
3. Timson, D. J. (2016). The structural biology of galactosemia. International Journal of Molecular Sciences, 17(7), 1028.
4. Isselbacher, K. J., Anderson, E. P., Kurahashi, K., & Kalckar, H. M. (1956). Congenital galactosemia, a single enzymatic block in galactose metabolism. Science, 123(3198), 635-636.
5. Coelho, A. I., Berry, G. T., & Rubio-Gozalbo, M. E. (2015). Galactosemia: old metabolite, new implications. Journal of Inherited Metabolic Disease, 38(3), 431-443.
6. Ning, C., & Segal, S. (2000). Plasma galactose-1-phosphate in galactoseemic patients. Journal of Inherited Metabolic Disease, 23(1), 32-38.
7. Leloir, L. F. (1951). The enzymatic transformation of uridine diphosphate glucose into a galactose derivative. Archives of Biochemistry and Biophysics, 33(2), 186-190.
8. McCorvie, T. J., & Timson, D. J. (2011). The structural and physiological basis of galactosemia. Biochimica et Biophysica Acta – Molecular Basis of Disease, 1812(11), 1385-1398.
9. Fridovich-Keil, J. L. (2006). Galactosemia: the good, the bad, and the unknown. Journal of Cellular Physiology, 209(3), 701-705.
10. Leslie, N. D. (2003). Insights into the pathogenesis of galactosemia. Annual Review of Nutrition, 23(1), 59-80.
2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide

Products Related to 2,3,4,6-Tetra-O-acetyl-β-D-glucopyranosyl azide can be found at Carbohydrates

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (1 vote)

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