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2-Deoxy-D-ribonic acid-1,4-lactone (Highly Pure)

Original price was: $995.00.Current price is: $495.00.

Catalog Number: B2013030 (50 mg)
2-Deoxy-D-ribonic acid-1,4-lactone (Highly Pure) is a high quality irreversible inhibitor of DNA polymerase. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

4.8/5 - (5 votes)

2-Deoxy-D-ribonic acid-1,4-lactone (Highly Pure)
Catalog number: B2013030
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 50 mg
Molecular Weight or Concentration: 132.1 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: 2DRA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Chakravorty S, Bhattacharya S, Chatzinotas A, Chakraborty W, Bhattacharya D, Gachhui R. Kombucha tea fermentation: Microbial and biochemical dynamics Int J Food Microbiol. 2016 Mar 2;220:63-72.
2: Abaci N, Senol Deniz FS, Orhan IE. Kombucha – An ancient fermented beverage with desired bioactivities: A narrowed review Food Chem X. 2022 Apr 6;14:100302.
3: Fittkau M, Voigt W, Holzhausen HJ, Schmoll HJ. Saccharic acid 1.4-lactone protects against CPT-11-induced mucosa damage in rats J Cancer Res Clin Oncol. 2004 Jul;130(7):388-94.
4: Geldsetzer J, Kalesse M. Towards the total synthesis of chondrochloren A: synthesis of the (Z)-enamide fragment Beilstein J Org Chem. 2020 Apr 14;16:670-673.
5: Iqbal S, Shaikh NN, Khan KM, Naz S, Ul-Haq Z, Perveen S, Choudhary MI. 2-Oxo-1,2,3,4-tetrahydropyrimidines Ethyl Esters as Potent β- Glucuronidase Inhibitors: One-pot Synthesis, In vitro and In silico Studies Med Chem. 2018;14(8):818-830.
6: Bhattacharya S, Manna P, Gachhui R, Sil PC. D-saccharic acid-1,4-lactone ameliorates alloxan-induced diabetes mellitus and oxidative stress in rats through inhibiting pancreatic β-cells from apoptosis via mitochondrial dependent pathway Toxicol Appl Pharmacol. 2011 Dec 1;257(2):272-83.
7: Horton D, Thomson JK, Varela O, Nin A, de Lederkremer RM. Confirmation of the structures of the products obtained on acylation of 2-amino-2-deoxy-D-gluconic acid Carbohydr Res. 1989 Oct 31;193:49-60.
8: Ko J, Hwang H, Chin J, Hahn D, Lee J, Yang I, Shin K, Ham J, Kang H. A stereo-controlled synthesis of 2,4-dimethyl-4-hydroxy-16-phenylhexadecanoic acid 1,4-lactone and its PPAR activities Bioorg Med Chem Lett. 2010 Oct 15;20(20):6017-9.
9: Bhattacharya S, Chatterjee S, Manna P, Das J, Ghosh J, Gachhui R, Sil PC. Prophylactic role of D-Saccharic acid-1,4-lactone in tertiary butyl hydroperoxide induced cytotoxicity and cell death of murine hepatocytes via mitochondria-dependent pathways J Biochem Mol Toxicol. 2011 Nov-Dec;25(6):341-54.
10: Bhattacharya S, Gachhui R, Sil PC. The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats Food Funct. 2013 Feb;4(2):283-96.

Products Related to 2-Deoxy-D-ribonic acid-1,4-lactone (Highly Pure) can be found at Chemicals

Additional Information

Weight 0.8 oz
Dimensions 2 × 0.9 × 0.9 in
4.8/5 - (5 votes)

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