1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate, 18:0-18:2 PA
Original price was: $2,395.00.$1,195.00Current price is: $1,195.00.
Catalog Number: B2018961 (5 mg)
1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate, or 18:0-18:2 PA, is a glycerolipid consisting of a glycerol backbone, two fatty acid chains, and a phosphate group. This lipid plays a role in cell signaling and membrane dynamics. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
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In stock
Product Description
1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate, 18:0-18:2 PA
Catalog number: B2018961
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 mg
Molecular Weight or Concentration: 723 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: 18:0-18:2 PA, 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate (sodium salt), PA(18:0/18:2(9Z,12Z)), 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate (sodium salt)
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Otoki Y, Yu D, Shen Q, Sahlas DJ, Ramirez J, Gao F, Masellis M, Swartz RH, Chan PC, Pettersen JA, Kato S, Nakagawa K, Black SE, Swardfager W, Taha AY. Quantitative Lipidomic Analysis of Serum Phospholipids Reveals Dissociable Markers of Alzheimer’s Disease and Subcortical Cerebrovascular Disease J Alzheimers Dis. 2023;93(2):665-682.
2: Sakane F, Mizuno S, Takahashi D, Sakai H. Where do substrates of diacylglycerol kinases come from? Diacylglycerol kinases utilize diacylglycerol species supplied from phosphatidylinositol turnover-independent pathways Adv Biol Regul. 2018 Jan;67:101-108.
3: Murakami Y, Murakami C, Hoshino F, Lu Q, Akiyama R, Yamaki A, Takahashi D, Sakane F. Palmitic acid- and/or palmitoleic acid-containing phosphatidic acids are generated by diacylglycerol kinase α in starved Jurkat T cells Biochem Biophys Res Commun. 2020 May 14;525(4):1054-1060.
4: Humes ST, Iovine N, Prins C, Garrett TJ, Lednicky JA, Coker ES, Sabo-Attwood T. Association between lipid profiles and viral respiratory infections in human sputum samples Respir Res. 2022 Jul 2;23(1):177.
5: Skotland T, Kavaliauskiene S, Sandvig K. The role of lipid species in membranes and cancer-related changes Cancer Metastasis Rev. 2020 Jun;39(2):343-360.
6: Tian Q, Mitchell BA, Zampino M, Ferrucci L. Longitudinal associations between blood lysophosphatidylcholines and skeletal muscle mitochondrial function Geroscience. 2022 Aug;44(4):2213-2221.
7: Guo L, Mishra G, Taylor K, Wang X. Phosphatidic acid binds and stimulates Arabidopsis sphingosine kinases J Biol Chem. 2011 Apr 15;286(15):13336-45.
8: Hoshino F, Sakane F. Polyunsaturated fatty acid-containing phosphatidic acids selectively interact with L-lactate dehydrogenase A and induce its secondary structural change and inactivation Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Oct;1865(10):158768.
9: Hoshino F, Sakane F. The SAC1 phosphatase domain of synaptojanin-1 is activated by interacting with polyunsaturated fatty acid-containing phosphatidic acids FEBS Lett. 2021 Oct;595(19):2479-2492.
10: Hirata T, Smith SV, Takahashi T, Miyata N, Roman RJ. Increased Levels of Renal Lysophosphatidic Acid in Rodent Models with Renal Disease J Pharmacol Exp Ther. 2021 Feb;376(2):240-249.
Products Related to 1-stearoyl-2-linoleoyl-sn-glycero-3-phosphate, 18:0-18:2 PA can be found at Lipids
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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