Xanthosine 3′,5′-cyclic Monophosphate

Description

Xanthosine 3′,5′-cyclic Monophosphate
Catalog number: B2014356
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 vial
Molecular Weight or Concentration: 367.2 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: cXMP
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Sigel H, Operschall BP, Griesser R. Xanthosine 5′-monophosphate (XMP). Acid-base and metal ion-binding properties of a chameleon-like nucleotide Chem Soc Rev. 2009 Aug;38(8):2465-94.
2: Kulikowska E, Kierdaszuk B, Shugar D. Xanthine, xanthosine and its nucleotides: solution structures of neutral and ionic forms, and relevance to substrate properties in various enzyme systems and metabolic pathways Acta Biochim Pol. 2004;51(2):493-531.
3: Oka N, Hirabayashi H, Kumada K, Ando K. Synthesis of xanthosine 2-phosphate diesters via phosphitylation of the carbonyl group Bioorg Med Chem Lett. 2021 Dec 15;54:128439.
4: Ahmed SA, Sarma P, Barge SR, Swargiary D, Devi GS, Borah JC. Xanthosine, a purine glycoside mediates hepatic glucose homeostasis through inhibition of gluconeogenesis and activation of glycogenesis via regulating the AMPK/ FoxO1/AKT/GSK3_ signaling cascade Chem Biol Interact. 2023 Feb 1;371:110347.
5: Rauner G, Barash I. Xanthosine administration does not affect the proportion of epithelial stem cells in bovine mammary tissue, but has a latent negative effect on cell proliferation Exp Cell Res. 2014 Oct 15;328(1):186-196.
6: Mair S, Erharter K, Renard E, Brillet K, Brunner M, Lusser A, Kreutz C, Ennifar E, Micura R. Towards a comprehensive understanding of RNA deamination: synthesis and properties of xanthosine-modified RNA Nucleic Acids Res. 2022 Jun 24;50(11):6038-6051.
7: Rttger K, Stellmacher R, Stuhldreier MC, Temps F. Ultrafast Electronic Deactivation Dynamics of Xanthosine Monophosphate Molecules. 2017 Jan 18;22(1):160.
8: Choudhary RK, Choudhary S, Verma R. In vivo response of xanthosine on mammary gene expression of lactating Beetal goat Mol Biol Rep. 2018 Aug;45(4):581-590.
9: Choudhary S, Li W, Bickhart D, Verma R, Sethi RS, Mukhopadhyay CS, Choudhary RK. Examination of the xanthosine response on gene expression of mammary epithelial cells using RNA-seq technology J Anim Sci Technol. 2018 Jul 13;60:18.
10: Baccolini C, Witte CP. AMP and GMP Catabolism in Arabidopsis Converge on Xanthosine, Which Is Degraded by a Nucleoside Hydrolase Heterocomplex Plant Cell. 2019 Mar;31(3):734-751.

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