Uridine 5′-diphospho-N-acetylglucosamine Sodium Salt
Original price was: $1,395.00.$695.00Current price is: $695.00.
Catalog Number: B2017831 (10 mg)
Uridine 5′-diphospho-N-acetylglucosamine Sodium Salt, also known as UDP-GlcNAc, is a nucleotide sugar that serves as a key building block in the biosynthesis of glycoproteins, glycolipids, and proteoglycans. It plays a crucial role in various cellular processes, including cell signaling, cell adhesion, and immune response. UDP-GlcNAc is involved in the modification of proteins through glycosylation, which is essential for proper protein folding, stability, and function. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.
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Product Description
Uridine 5′-diphospho-N-acetylglucosamine Sodium Salt
Catalog number: B2017831
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 mg
Molecular Weight or Concentration: 651.32 g/mol
Supplied as: Powder
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: UDP-GlcNAc, UDP-N-acetylglucosamine, UDPAG
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
References:
1: Goodwin OY, Thomasson MS, Lin AJ, Sweeney MM, Macnaughtan MA. E. coli sabotages the in vivo production of O-linked β-N-acetylglucosamine-modified proteins J Biotechnol. 2013 Dec;168(4):315-23.
2: Chan J, Lee KH. Effect of uridine diphospho-N-acetylglucosamine and sodium salicylate on L-glutamine-D-fructose-6-phosphate aminotransferase activity from rat gastric mucosa J Pharm Sci. 1975 Jul;64(7):1182-5.
3: Wagner RR, Cynkin MA. A procedure for the synthesis of uridine-5′-diphospho-N-acetylglucosamine-14C Anal Biochem. 1968 Oct 24;25(1):572-7.
4: Okuyama K, Hamamoto T, Ishige K, Takenouchi K, Noguchi T. An efficient method for production of uridine 5′-diphospho-N-acetylglucosamine Biosci Biotechnol Biochem. 2000 Feb;64(2):386-92.
5: Nishikawa J, Iwawaki H, Takubo Y, Nishihara T, Kondo M. Appearance of uridine 5′-diphospho-N-acetylglucosamine-4-epimerase during sporulation of Bacillus megaterium Microbiol Immunol. 1986;30(11):1085-93.
6: Zhou J, Fan L, Wei P, Huang L, Cai J, Xu Z. Efficient production of uridine 5′-diphospho-N-acetylglucosamine by the combination of three recombinant enzymes and yeast cells Prep Biochem Biotechnol. 2010;40(4):294-304.
7: Mahour R, Klapproth J, Rexer TFT, Schildbach A, Klamt S, Pietzsch M, Rapp E, Reichl U. Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine J Biotechnol. 2018 Oct 10;283:120-129.
8: Wells L, Vosseller K, Hart GW. A role for N-acetylglucosamine as a nutrient sensor and mediator of insulin resistance Cell Mol Life Sci. 2003 Feb;60(2):222-8.
9: Hauser SC, Ransil BJ, Ziurys JC, Gollan JL. Interaction of uridine 5′-diphosphoglucuronic acid with microsomal UDP-glucuronosyltransferase in primate liver: the facilitating role of uridine 5′-diphospho-N-acetylglucosamine Biochim Biophys Acta. 1988 Nov 17;967(2):141-8.
10: Liu HD, Li YM, Du JT, Hu J, Zhao YF. Novel acetylation-aided migrating rearrangement of uridine-diphosphate-N-acetylglucosamine in electrospray ionization multistage tandem mass spectrometry J Mass Spectrom. 2006 Feb;41(2):208-15.
Products Related to Uridine 5′-diphospho-N-acetylglucosamine Sodium Salt can be found at Chemicals
Additional Information
| Weight | 0.15 oz |
|---|---|
| Dimensions | 2 × 0.5 × 0.5 in |
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