Tyr-Ile-Gly-Ser-Arg (Highly Pure)

Description

Tyr-Ile-Gly-Ser-Arg
Catalog number: B2014306
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 594.66 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: Laminin Fragment 929-933
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Massia SP, Hubbell JA. Covalent surface immobilization of Arg-Gly-Asp- and Tyr-Ile-Gly-Ser-Arg-containing peptides to obtain well-defined cell-adhesive substrates Anal Biochem. 1990 Jun;187(2):292-301.
2: Massia SP, Rao SS, Hubbell JA. Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin J Biol Chem. 1993 Apr 15;268(11):8053-9.
3: Nomizu M, Yamamura K, Kleinman HK, Yamada Y. Multimeric forms of Tyr-Ile-Gly-Ser-Arg (YIGSR) peptide enhance the inhibition of tumor growth and metastasis Cancer Res. 1993 Aug 1;53(15):3459-61.
4: Saiki I, Murata J, Iida J, Sakurai T, Nishi N, Matsuno K, Azuma I. Antimetastatic effects of synthetic polypeptides containing repeated structures of the cell adhesive Arg-Gly-Asp (RGD) and Tyr-Ile-Gly-Ser-Arg (YIGSR) sequences Br J Cancer. 1989 Nov;60(5):722-8.
5: Yoshida N, Ishii E, Nomizu M, Yamada Y, Mohri S, Kinukawa N, Matsuzaki A, Oshima K, Hara T, Miyazaki S. The laminin-derived peptide YIGSR (Tyr-Ile-Gly-Ser-Arg) inhibits human pre-B leukaemic cell growth and dissemination to organs in SCID mice Br J Cancer. 1999 Aug;80(12):1898-904.
6: Rosellini E, Barbani N, Giusti P, Ciardelli G, Cristallini C. Molecularly imprinted nanoparticles with recognition properties towards a laminin H-Tyr-Ile-Gly-Ser-Arg-OH sequence for tissue engineering applications Biomed Mater. 2010 Dec;5(6):065007.
7: Nishiyama Y, Yoshikawa T, Kurita K, Hojo K, Kamada H, Tsutsumi Y, Mayumi T, Kawasaki K. Regioselective conjugation of chitosan with a laminin-related peptide, Tyr-Ile-Gly-Ser-Arg, and evaluation of its inhibitory effect on experimental cancer metastasis Chem Pharm Bull (Tokyo). 1999 Mar;47(3):451-3.
8: Iwamoto Y, Nomizu M, Yamada Y, Ito Y, Tanaka K, Sugioka Y. Inhibition of angiogenesis, tumour growth and experimental metastasis of human fibrosarcoma cells HT1080 by a multimeric form of the laminin sequence Tyr-Ile-Gly-Ser-Arg (YIGSR) Br J Cancer. 1996 Mar;73(5):589-95.
9: Saiki I, Murata J, Iida J, Nishi N, Sugimura K, Azuma I. The inhibition of murine lung metastasis by synthetic polypeptides [poly(arg-gly-asp) and poly(tyr-ile-gly-ser-arg)] with a core sequence of cell adhesion molecules Br J Cancer. 1989 Feb;59(2):194-7.
10: Hojo K, Manabe Y, Uda T, Tsuda Y. Water-Based Solid-Phase Peptide Synthesis without Hydroxy Side Chain Protection J Org Chem. 2022 Sep 2;87(17):11362-11368.

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