Staurosporine from Streptomyces sp.


Catalog Number: B2013830 (100 ug)
Staurosporine from Streptomyces sp. is a high quality reversible, ATP-competitive and broad spectrum inhibitor of protein kinases. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Staurosporine from Streptomyces sp.
Catalog number: B2013830
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 ug
Molecular Weight or Concentration: 466.53 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: Staurosporine, Streptomyces sp., PKA Inhibitor II, MLCK Inhibitor
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Stevanovic M, D’Agostino PM, Mojicevic M, Gulder TAM, Nikodinovic-Runic J, Vojnovic S. Streptomyces sp. BV410: Interspecies cross-talk for staurosporine production J Appl Microbiol. 2022 Oct;133(4):2560-2568.
2: Mojicevic M, D’Agostino PM, Pavic A, Vojnovic S, Senthamaraikannan R, Vasiljevic B, Gulder TAM, Nikodinovic-Runic J. Streptomyces sp. BV410 isolate from chamomile rhizosphere soil efficiently produces staurosporine with antifungal and antiangiogenic properties Microbiologyopen. 2020 Mar;9(3):e986.
3: Zhou B, Hu ZJ, Zhang HJ, Li JQ, Ding WJ, Ma ZJ. Bioactive staurosporine derivatives from the Streptomyces sp. NB-A13 Bioorg Chem. 2019 Feb;82:33-40.
4: Khosravi Babadi Z, Ebrahimipour G, Wink J, Narmani A, Risdian C. Isolation and identification of Streptomyces sp. Act4Zk, a good producer of Staurosporine and some derivatives Lett Appl Microbiol. 2021 Feb;72(2):206-218.
5: Cheng J, Park SB, Kim SH, Yang SH, Suh JW, Lee CH, Kim JG. Suppressing activity of staurosporine from Streptomyces sp. MJM4426 against rice bacterial blight disease J Appl Microbiol. 2016 Apr;120(4):975-85.
6: Kim BY, Zucchi TD, Fiedler HP, Goodfellow M. Streptomyces staurosporininus sp. nov., a staurosporine-producing actinomycete Int J Syst Evol Microbiol. 2012 Apr;62(Pt 4):966-970.
7: Cui T, Lin S, Wang Z, Fu P, Wang C, Zhu W. Cytotoxic Indolocarbazoles From a Marine-Derived Streptomyces Sp. OUCMDZ-5380 Front Microbiol. 2022 Jul 12;13:957473.
8: Li X, Huang P, Wang Q, Xiao L, Liu M, Bolla K, Zhang B, Zheng L, Gan B, Liu X, Zhang L, Zhang X. Staurosporine_ from the endophytic Streptomyces sp. strain CNS-42 acts as a potential biocontrol agent and growth elicitor in cucumber Antonie Van Leeuwenhoek. 2014 Sep;106(3):515-25.
9: Li XB, Tang JS, Gao H, Ding R, Li J, Hong K, Yao XS. A new staurosporine analog from Actinomycetes Streptomyces sp. (172614) J Asian Nat Prod Res. 2011 Aug;13(8):765-9.
10: Chen YY, Chen LY, Chen PJ, El-Shazly M, Peng BR, Chen YC, Su CH, Su JH, Sung PJ, Yen PT, Wang LS, Lai KH. Probing Anti-Leukemic Metabolites from Marine-Derived Streptomyces sp. LY1209 Metabolites. 2022 Apr 2;12(4):320.

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Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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