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Sodium glycodeoxycholate (Highly Pure)

$195.00

Catalog Number: B2010641 (250 mg)
Sodium glycodeoxycholate (Highly Pure) is a highly pure anionic bile salt. This product has been used as molecular tool in the study of the biochemistry of bile salt micelles. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: B2010641 Categories: ,

Description

Sodium glycodeoxycholate (Highly Pure)
Catalog number: B2010641
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 250 mg
Molecular Weight or Concentration: 471.61 g/mol
Supplied as: Powder
Applications: molecular tool in the study of the biochemistry of bile salt micelles
Storage: RT
Keywords: N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine, Glycodeoxycholic acid sodium salt, 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Glycodesoxycholic acid
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Brayden DJ, Stuettgen V. Sodium glycodeoxycholate and sodium deoxycholate as
epithelial permeation enhancers: in vitro and ex vivo intestinal and buccal
bioassays. Eur J Pharm Sci. 2021 Apr 1;159:105737.

2: Zhou H, Hylemon PB. Bile acids are nutrient signaling hormones. Steroids.
2014 Aug;86:62-8.

3: de Petris G, Festa MR, Galantini L, Giglio E, Leggio C, Pavel NV, Troiani A.
Sodium glycodeoxycholate and glycocholate mixed aggregates in gas and solution
phases. J Phys Chem B. 2009 May 21;113(20):7162-9.

4: Chang Y, Cardinal JR. Light-scattering studies on bile acid salts II: pattern
of self-association of sodium deoxycholate, sodium taurodeoxycholate, and sodium
glycodeoxycholate in aqueous electrolyte solutions. J Pharm Sci. 1978
Jul;67(7):994-9.

5: Bayati S, Galantini L, Knudsen KD, Schillén K. Effects of Bile Salt Sodium
Glycodeoxycholate on the Self-Assembly of PEO-PPO-PEO Triblock Copolymer P123 in
Aqueous Solution. Langmuir. 2015 Dec 22;31(50):13519-27.

6: Bottari E, Festa MR. Composition of aqueous solutions containing sodium
glycocholate and glycodeoxycholate. Ann Chim. 2005 Nov-Dec;95(11-12):791-802.

7: Cozzolino S, Galantini L, Giglio E, Hoffmann S, Leggio C, Pavel NV. Structure
of sodium glycodeoxycholate micellar aggregates from small-angle X-ray
scattering and light-scattering techniques. J Phys Chem B. 2006 Jun
29;110(25):12351-9.

8: Brown BD, Ammon HV. Effect of glucose on jejunal water and solute absorption
in the presence of glycodeoxycholate and oleate in man. Dig Dis Sci. 1981
Aug;26(8):710-7.

9: Wilson FA, Treanor LL. Glycodeoxycholate transport in brush border membrane
vesicles isolated from rat jejunum and ileum. Biochim Biophys Acta. 1979 Jul
5;554(2):430-40.
10: Hoogstraate AJ, Coos Verhoef J, Pijpers A, van Leengoed LA, Verheijden JH,
Junginger HE, Boddé HE. In vivo buccal delivery of the peptide drug buserelin
with glycodeoxycholate as an absorption enhancer in pigs. Pharm Res. 1996
Aug;13(8):1233-7.

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