S6 Kinase Substrate (229-239)

Product Description

S6 Kinase Substrate (229-239)
Catalog number: B2011489
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1313.6 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: S6 Kinase Substrate
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Magnuson B, Ekim B, Fingar DC. Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks Biochem J. 2012 Jan 1;441(1):1-21.
2: Fan Y, Cheng Y, Li Y, Chen B, Wang Z, Wei T, Zhang H, Guo Y, Wang Q, Wei Y, Chen F, Sha J, Guo X, Wang L. Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of Checkpoint Kinase 1 via Activating Mammalian Target of Rapamycin C1/Ribosomal Protein S6 Kinase b-1 Pathway Circulation. 2020 May 12;141(19):1554-1569.
3: Yaguchi M, Ikeya S, Kozaki A. The activation mechanism of plant S6 kinase (S6K), a substrate of TOR kinase, is different from that of mammalian S6K FEBS Lett. 2020 Feb;594(4):776-787.
4: Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, Pende M. ZRF1 is a novel S6 kinase substrate that drives the senescence programme EMBO J. 2017 Mar 15;36(6):736-750.
5: Xu J, Jia Q, Zhang Y, Yuan Y, Xu T, Yu K, Chai J, Wang K, Chen L, Xiao T, Li M. Prominent roles of ribosomal S6 kinase 4 (RSK4) in cancer Pathol Res Pract. 2021 Mar;219:153374.
6: Sok P, Gógl G, Kumar GS, Alexa A, Singh N, Kirsch K, Sebő A, Drahos L, Gáspári Z, Peti W, Reményi A. MAP Kinase-Mediated Activation of RSK1 and MK2 Substrate Kinases Structure. 2020 Oct 6;28(10):1101-1113.e5.
7: Li C, Ma B, Chen J, Jeong Y, Xu X. Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling Mar Drugs. 2020 Sep 28;18(10):495.
8: Bhatt AP, Wong JP, Weinberg MS, Host KM, Giffin LC, Buijnink J, van Dijk E, Izumiya Y, Kung HJ, Temple BR, Damania B. A viral kinase mimics S6 kinase to enhance cell proliferation Proc Natl Acad Sci U S A. 2016 Jul 12;113(28):7876-81.
9: Das F, Maity S, Ghosh-Choudhury N, Kasinath BS, Ghosh Choudhury G. Deacetylation of S6 kinase promotes high glucose-induced glomerular mesangial cell hypertrophy and matrix protein accumulation J Biol Chem. 2019 Jun 14;294(24):9440-9460.
10: Flotow H, Thomas G. Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver J Biol Chem. 1992 Feb 15;267(5):3074-8.

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