ß-hydroxybutyric Acid (BHB) for Interference Testing

Description

ß-hydroxybutyric Acid (BHB) for Interference Testing
Catalog number: C2010425
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 500 mg
Molecular Weight or Concentration: 126.09 (g/mol)
Supplied as: Powder
Appearance: White solid
Applications: ketone body present in the epithelium of liver cells. This compound interconversion to acetoacetate is involved in the acid-base balance. Its blood levels can help in the assessment of metabolic energy deficits.
Storage: Room Temperature
Keywords: (±)-3-Hydroxybutanoic acid sodium salt, DL-β-Hydroxybutyric acid sodium salt, BHB, beta-hydroxybutyric acid, acetone body
Grade: Biotechnology grade. All solid components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Lima MS, Cota JB, Vaz YM, Ajuda IG, Pascoal RA, Carolino N, Hjerpe CA.
Glucose intolerance in dairy goats with pregnancy toxemia: Lack of correlation
between blood pH and beta hydroxybutyric acid values. Can Vet J. 2016
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2: Shaw DM, Merien F, Braakhuis A, Maunder ED, Dulson DK. Effect of a Ketogenic
Diet on Submaximal Exercise Capacity and Efficiency in Runners. Med Sci Sports
Exerc. 2019 Oct;51(10):2135-2146.

3: Kraus FB, Kocijancic M, Kluttig A, Ludwig-Kraus B. Test validation, method
comparison and reference range for the measurement of β-hydroxybutyrate in
peripheral blood samples. Biochem Med (Zagreb). 2020 Feb 15;30(1):010707.

4: Jensen NJ, Nilsson M, Ingerslev JS, Olsen DA, Fenger M, Svart M, Møller N,
Zander M, Miskowiak KW, Rungby J. Effects of β-hydroxybutyrate on cognition in
patients with type 2 diabetes. Eur J Endocrinol. 2020 Feb;182(2):233-242.

5: Dirksen G, Breitner W. A new quick-test for semiquantitative determination of
beta-hydroxybutyric acid in bovine milk. Zentralbl Veterinarmed A. 1993 Nov-
Dec;40(9-10):779-84.

6: Timmons JA, Myer P, Maturen A, Webster R, Schaller E, Leikin J, Barkin R. Use
of beta-hydroxybutyric acid levels in the emergency department. Am J Ther. 1998
May;5(3):159-63.

7: Evans M, Egan B. Intermittent Running and Cognitive Performance after Ketone
Ester Ingestion. Med Sci Sports Exerc. 2018 Nov;50(11):2330-2338.

8: Sahagun E, Ward LM, Kinzig KP. Attenuation of stress-induced weight loss with
a ketogenic diet. Physiol Behav. 2019 Dec 1;212:112654.

9: Mahrt A, Burfeind O, Heuwieser W. Effects of time and sampling location on
concentrations of β-hydroxybutyric acid in dairy cows. J Dairy Sci.
2014;97(1):291-8.
10: Panousis N, Brozos Ch, Karagiannis I, Giadinis ND, Lafi S, Kritsepi-
Konstantinou M. Evaluation of Precision Xceed® meter for on-site monitoring of
blood β-hydroxybutyric acid and glucose concentrations in dairy sheep. Res Vet
Sci. 2012 Aug;93(1):435-9.

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