Renin FRET Substrate

Product Description

Renin FRET Substrate
Catalog number: B2011308
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 0.1 mg
Molecular Weight or Concentration: 2100 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: 5-FAM QXL520
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
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2: Lu X, Krop M, Batenburg WW, Musterd-Bhaggoe UM, Garrelds IM, Danser AH. Renin inhibitor VTP-27999 differs from aliskiren: focus on their intracellular accumulation and the (pro)renin receptor J Hypertens. 2014 Jun;32(6):1255-63.
3: Ramanathan G, Elumalai R, Periyasamy S, Lakkakula BV. Renin gene rs1464816 polymorphism contributes to chronic kidney disease progression in ADPKD J Biomed Sci. 2016 Jan 11;23:1.
4: Gorris HH. Kinetic analysis of renin and its inhibitors by detecting double-labelled peptidic substrates with an immunoassay Analyst. 2013 Apr 7;138(7):2104-9.
5: Iwai M, Senba I, Kanno H, Nakaoka H, Inaba S, Horiuchi M. Renin inhibitors inhibited the activity of recombinant human renin but not activity in healthy human plasma Clin Lab. 2012;58(3-4):291-8.
6: Schmiedt CW, Hurley KA, Tong X, Rakhmanova VA, Po CL, Hurley DJ. Measurement of plasma renin concentration in cats by use of a fluorescence resonance energy transfer peptide substrate of renin Am J Vet Res. 2009 Nov;70(11):1315-22.
7: Lu J, Sun PD. High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity J Biol Chem. 2020 Dec 25;295(52):18579-18588.
8: Naing SH, Vukoti KM, Drury JE, Johnson JL, Kalyoncu S, Hill SE, Torres MP, Lieberman RL. Catalytic Properties of Intramembrane Aspartyl Protease Substrate Hydrolysis Evaluated Using a FRET Peptide Cleavage Assay ACS Chem Biol. 2015 Sep 18;10(9):2166-74.
9: Hamada T, Kotani K, Nagai N, Tsuzaki K, Sano Y, Matsuoka Y, Fujibayashi M, Kiyohara N, Tanaka S, Yoshimura M, Egawa K, Kitagawa Y, Kiso Y, Moritani T, Sakane N. Genetic polymorphisms of the renin-angiotensin system and obesity-related metabolic changes in response to low-energy diets in obese women Nutrition. 2011 Jan;27(1):34-39.
10: Gnanasambandan R, Elumalai R, Soundararajan P, Lakkakula BVKS. Angiotensinogen gene polymorphisms and progression of chronic kidney disease in ADPKD patients Clin Exp Nephrol. 2016 Aug;20(4):561-568.

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