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Renin FRET Substrate Dabcyl EDANS

Original price was: $1,395.00.Current price is: $695.00.

Catalog Number: B2011484 (1 mg)
Renin FRET Substrate Dabcyl EDANS is a high quality substrate with a renin cleavage site at the N-terminus of human angiotensinogen. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Product Description

4.8/5 - (6 votes)

Renin FRET Substrate Dabcyl EDANS
Catalog number: B2011484
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1798.2 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Renin FRET substrate, Dabcyl/EDANS
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Sparks MA, Crowley SD, Gurley SB, Mirotsou M, Coffman TM. Classical Renin-Angiotensin system in kidney physiology Compr Physiol. 2014 Jul;4(3):1201-28.
2: Tamura K, Nyui N, Nakamaru M, Gotoh E. [Angiotensinogen (renin substrate)] Nihon Rinsho. 1995 Mar;53 Su Pt 2:692-4.
3: Gordon DB. The role of renin substrate in hypertension Hypertension. 1983 May-Jun;5(3):353-62.
4: Takimoto-Ohnishi E, Murakami K. Renin-angiotensin system research: from molecules to the whole body J Physiol Sci. 2019 Jul;69(4):581-587.
5: Fyhrquist F, Rosenlöf K, Grönhagen-Riska C, Hortling L, Tikkanen I. Is renin substrate an erythropoietin precursor? Nature. 1984 Apr 12-18;308(5960):649-52.
6: Burns KD, Homma T, Harris RC. The intrarenal renin-angiotensin system Semin Nephrol. 1993 Jan;13(1):13-30.
7: McDonald WJ, Cohen EL, Lucas CP, Conn JW. Renin-renin substrate kinetic constants in the plasma of normal and estrogen-treated humans J Clin Endocrinol Metab. 1977 Dec;45(6):1297-304.
8: Kokubu T, Hiwada K, Yamamura Y. Effects of unilateral nephrectomy on plasma renin substrate and renin concentration in rats Pflugers Arch. 1975 Aug 12;358(4):303-10.
9: Yamashita S, Shibata N, Boku-Ikeda A, Abe E, Inayama A, Yamaguchi T, Higuma A, Inagaki K, Tsuyuzaki T, Iwamoto S, Ohno S, Yokogawa T, Nishikawa K, Biswas KB, Nabi AH, Nakagawa T, Suzuki F, Ebihara A. Escherichia coli-based production of recombinant ovine angiotensinogen and its characterization as a renin substrate BMC Biotechnol. 2016 Apr 7;16:33.
10: Yan Y, Zhou A, Carrell RW, Read RJ. Structural basis for the specificity of renin-mediated angiotensinogen cleavage J Biol Chem. 2019 Feb 15;294(7):2353-2364.

Products Related to Renin FRET Substrate Dabcyl EDANS can be found at Substrates

Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
4.8/5 - (6 votes)

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