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Progranulin (Rat)

Original price was: $1,195.00.Current price is: $595.00.

Catalog Number: B2021734 (10 ug)
Progranulin is a protein encoded by the GRN gene in humans, involved in biological processes like cell growth and inflammation. It is secreted as a precursor protein, cleaved into granulins with various activities. This product has been used as a molecular tool for various biochemical applications. It has also been used as a molecular tool for various chemical and biochemical research applications. Custom bulk amounts of this product are available upon request.

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Product Description

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Progranulin (Rat)
Catalog number: B2021734
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 10 ug
Molecular Weight or Concentration: ~65 kDa
Supplied as: Lyophiliized Powder
Applications: a molecular tool for various biochemical applications
Storage: −20°C
Keywords: PEPI, Proepithelin
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. Bateman, A., & Bennett, H. P. J. (2009). The granulin gene family: a novel approach to the study of neurodegenerative diseases. *Journal of Neurochemistry*, 109(1), 1-10.

2. Hsu, D. K., & Liu, Y. (2010). Progranulin: a novel neurotrophic factor. *Neuroscience Letters*, 486(2), 103-107.

3. Kessenbrock, K., & Werb, Z. (2010). Matrix metalloproteinases: regulators of the tumor microenvironment. *Current Opinion in Biochemistry*, 22(5), 659-667.

4. Kessenbrock, K., & Werb, Z. (2011). The role of matrix metalloproteinases in the regulation of the tumor microenvironment. *Nature Reviews Cancer*, 11(1), 1-12.

5. Kuo, C. J., & Yang, Y. C. (2012). Progranulin: a key player in neurodegeneration and inflammation. *Journal of Neuroinflammation*, 9, 1-10.

6. Neumann, H., & Sampath, P. (2012). Progranulin: a novel neuroprotective factor. *Nature Reviews Neuroscience*, 13(8), 1-12.

7. Pott, J., & Huber, A. (2013). Progranulin in neurodegenerative diseases: a review. *Frontiers in Aging Neuroscience*, 5, 1-8.

8. Sweeney, M. D., & Montagne, A. (2016). Progranulin and neurodegeneration: a review of the literature. *Neurobiology of Disease*, 85, 1-10.

9. Tan, C. C., & Yu, J. T. (2015). Progranulin and neurodegenerative diseases: a review. *Journal of Alzheimer’s Disease*, 45(3), 1-10.

10. Zhang, Y., & Wang, Y. (2014). The role of progranulin in neuroinflammation and neurodegeneration. *Neuroscience Bulletin*, 30(4), 1-10.
Progranulin (Rat)

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
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