Phosphorylated UOM9 PKC Substrate

Product Description

Phosphorylated UOM9 PKC Substrate
Catalog number: B2011345
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 1422.5 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: UOM9, PKC Substrate, phosphorylated
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Siriwardena SU, Munkanatta Godage DNP, Shoba VM, Lai S, Shi M, Wu P, Chaudhary SK, Schreiber SL, Choudhary A. Phosphorylation-Inducing Chimeric Small Molecules J Am Chem Soc. 2020 Aug 19;142(33):14052-14057.
2: Qvit N, Kornfeld OS, Mochly-Rosen D. Engineered Substrate-Specific Delta PKC Antagonists to Enhance Cardiac Therapeutics Angew Chem Int Ed Engl. 2016 Dec 12;55(50):15672-15679.
3: Cloete I, Corrêa-Velloso JC, Bartlett PJ, Kirk V, Thomas AP, Sneyd J. A Tale of two receptors J Theor Biol. 2021 Jun 7;518:110629.
4: Sah P, Nelson NH, Shaw JH, Lutter EI. Chlamydia trachomatis recruits protein kinase C during infection Pathog Dis. 2019 Aug 1;77(6):ftz061.
5: Engin A. Human Protein Kinases and Obesity Adv Exp Med Biol. 2017;960:111-134.
6: Chapline C, Cottom J, Tobin H, Hulmes J, Crabb J, Jaken S. A major, transformation-sensitive PKC-binding protein is also a PKC substrate involved in cytoskeletal remodeling J Biol Chem. 1998 Jul 31;273(31):19482-9.
7: Dekker LV, McIntyre P, Parker PJ. Altered substrate selectivity of PKC-eta pseudosubstrate site mutants FEBS Lett. 1993 Aug 23;329(1-2):129-33.
8: Walsh MP, Horowitz A, Clément-Chomienne O, Andrea JE, Allen BG, Morgan KG. Protein kinase C mediation of Ca(2+)-independent contractions of vascular smooth muscle Biochem Cell Biol. 1996;74(4):485-502.
9: Verma SK, Ganesan TS, Parker PJ. The tumour suppressor RASSF1A is a novel substrate of PKC FEBS Lett. 2008 Jun 25;582(15):2270-6.
10: Ringvold HC, Khalil RA. Protein Kinase C as Regulator of Vascular Smooth Muscle Function and Potential Target in Vascular Disorders Adv Pharmacol. 2017;78:203-301.

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