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Nojirimycin Bisulfite

$295.00

Catalog Number: MDP0889 (1 mg)
Nojirimycin Bisulfite is a highly pure glycosidase inhibitor. This product has been used as potent inhibitor of glucosidase. It has also been used in a wide array of other biochemical and immunological applications. Custom bulk amounts of this product are available upon request.

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SKU: MDP0889 Categories: ,

Description

Nojirimycin Bisulfite
Catalog number: MDP0889
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 243.23 g/mol
Supplied as: Powder
Applications: potent inhibitor of glucosidase
Storage: -20°C
Keywords: 5-Amino-5-Deoxy-Glucopyranose Bisulfite, Nojirimycin 1-sulfonic acid
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.
Indication for Use: This product is for Research Use Only. This product is NOT for human or animal use.

References:
1: Hyun SB, Chung YC, Hyun C-. Nojirimycin suppresses inflammation via
regulation of NF-κ B signaling pathways. Pharmazie. 2020 Dec 1;75(12):637-641.

2: Okazawa A, Wakabayashi T, Muranaka T, Sugimoto Y, Ohta D. The effect of
nojirimycin on the transcriptome of germinating Orobanche minor seeds. J
Pestic Sci. 2020 Nov 20;45(4):230-237.

3: Cuffaro D, Landi M, D’Andrea F, Guazzelli L. Preparation of 1,6-di-deoxy-d-
galacto and 1,6-di-deoxy-l-altro nojirimycin derivatives by aminocyclization of
a 1,5-dicarbonyl derivative. Carbohydr Res. 2019 Aug 1;482:107744.

4: Tsuruoka T, Fukuyasu H, Ishii M, Usui T, Shibahara S, Inouye S. Inhibition of
mouse tumor metastasis with nojirimycin-related compounds. J Antibiot (Tokyo).
1996 Feb;49(2):155-61.

5: Viuff AH, Besenbacher LM, Kamori A, Jensen MT, Kilian M, Kato A, Jensen HH.
Stable analogues of nojirimycin–synthesis and biological evaluation of
nojiristegine and manno-nojiristegine. Org Biomol Chem. 2015 Oct
7;13(37):9637-58.

6: Bini D, Cardona F, Forcella M, Parmeggiani C, Parenti P, Nicotra F, Cipolla
L. Synthesis and biological evaluation of nojirimycin- and pyrrolidine-based
trehalase inhibitors. Beilstein J Org Chem. 2012;8:514-21.

7: Chambers JP, Elbein AD, Williams JC. Nojirimycin-a potent inhibitor of
purified lysosomal alpha-glucosidase from human liver. Biochem Biophys Res
Commun. 1982 Aug 31;107(4):1490-6.

8: Harada K, Kurono Y, Nagasawa S, Oda T, Nasu Y, Wakabayashi T, Sugimoto Y,
Matsuura H, Muranaka S, Hirata K, Okazawa A. Enhanced production of nojirimycin
viaStreptomyces ficellus cultivation using marine broth and
inhibitory activity of the culture for seeds of parasitic weeds. J Pestic Sci.
2017 Nov 24;42(4):166-171.
9: Brumshtein B, Aguilar-Moncayo M, Benito JM, García Fernandez JM, Silman I,
Shaaltiel Y, Aviezer D, Sussman JL, Futerman AH, Ortiz Mellet C. Cyclodextrin-
mediated crystallization of acid β-glucosidase in complex with amphiphilic
bicyclic nojirimycin analogues. Org Biomol Chem. 2011 Jun 7;9(11):4160-7.


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