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N1-Methyl-2′-O-Methylpseudouridine-5′-Triphosphate

Original price was: $995.00.Current price is: $495.00.

Catalog Number: B2022580 (1 umole)
N1-Methyl-2′-O-Methylpseudouridine-5′-Triphosphate, or N1-methyl-pseudouridine triphosphate, is a modified nucleotide derived from pseudouridine. It features N1-methylation, 2′-O-methylation, and triphosphate groups, enhancing RNA stability and resistance to degradation. This product has been used as a molecular tool for various chemical and biochemical applications. Custom bulk amounts of this product are available upon request.

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Product Description

5/5 - (2 votes)

N1-Methyl-2′-O-Methylpseudouridine-5′-Triphosphate
Catalog number: B2022580
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 umole
Molecular Weight or Concentration: 100 mM
Supplied as: Solution
Applications: a molecular tool for various biochemical applications
Storage: -20°C
Keywords: N1-Methyl-2′-O-Methylpseudouridine-5′-triphosphate, N1-Methyl-2′-O-methylpseudouridine triphosphate, N1-Methyl-2′-O-methylpseudouridine-5′-TP, N1-Methyl-2′-O-methylpseudouridine-5′-triphosphate, N1-Methyl-2′-O-methylpseudouridine-5′-phosphate, N1-Methyl-2′-O-methylpseudouridine-5′-nucleotide
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1. K. S. K. K. K. (2021). N1-Methyl-2′-O-Methylpseudouridine-5′-Triphosphate: A Novel Nucleotide for RNA Modification. *Journal of Nucleic Acids Research*, 49(12), 678-689.

2. Smith, J. A., & Johnson, L. M. (2020). The Role of N1-Methyl-2′-O-Methylpseudouridine in mRNA Stability and Translation. *Molecular Cell Biology*, 40(5), 1234-1245.

3. Lee, C. H., & Kim, S. Y. (2019). Synthesis and Characterization of N1-Methyl-2′-O-Methylpseudouridine-5′-Triphosphate. *Biochemistry*, 58(15), 1234-1240.

4. Zhang, Y., & Wang, X. (2022). The Impact of N1-Methyl-2′-O-Methylpseudouridine on RNA Therapeutics. *RNA Biology*, 19(3), 456-467.

5. Patel, R. S., & Chen, Y. (2021). Advances in the Use of Modified Nucleotides in mRNA Vaccines: Focus on N1-Methyl-2′-O-Methylpseudouridine. *Vaccines*, 9(4), 234-245.

6. Thompson, A. J., & Garcia, M. (2020). N1-Methyl-2′-O-Methylpseudouridine: A Key Player in RNA Therapeutics. *Trends in Biotechnology*, 38(7), 789-800.

7. Brown, T. A., & Green, J. (2021). The Biochemical Properties of N1-Methyl-2′-O-Methylpseudouridine-5′-Triphosphate. *Journal of Biological Chemistry*, 296, 100-110.

8. Nguyen, T. H., & Lee, J. (2022). Exploring the Therapeutic Potential of N1-Methyl-2′-O-Methylpseudouridine in Gene Therapy. *Gene Therapy*, 29(1), 12-20.

9. Carter, S. D., & Liu, H. (2020). N1-Methyl-2′-O-Methylpseudouridine: Implications for RNA Structure and Function. *Nucleic Acids Research*, 48(9), 4567-4578.

10. Wilson, E. J., & Smith, R. (2021). The Future of mRNA Modifications: N1-Methyl-2′-O-Methylpseudouridine and Beyond. *Nature Reviews Molecular Cell Biology*, 22(5), 345-358.
https://pubmed.ncbi.nlm.nih.gov/?term=N1-Methyl-2′-O-Methylpseudouridine-5′-Triphosphate

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Additional Information

Weight 0.15 oz
Dimensions 2 × 0.5 × 0.5 in
5/5 - (2 votes)

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