Methoxyresorufin (Highly Pure)

Product Description

Methoxyresorufin (Highly Pure)
Catalog number: B2011455
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 2.5 mg
Molecular Weight or Concentration: 227.2 g/mol
Supplied as: Lyophilized
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Resorufin methyl ether
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Hamm JT, Ross DG, Richardson VM, Diliberto JJ, Birnbaum LS. Methoxyresorufin: an inappropriate substrate for CYP1A2 in the mouse Biochem Pharmacol. 1998 Dec 15;56(12):1657-60.
2: Murcia H, Cruz A, León J, González-Curbelo MÁ. Study on the inhibitory effect of furafylline and troleandomycin in the 7-methoxyresorufin-O-demethylase and nifedipine oxidase activities in hepatic microsomes from four poultry species using high-performance liquid chromatography coupled with fluorescence and ultraviolet detection J Pharm Biomed Anal. 2019 Feb 5;164:148-154.
3: Nerurkar PV, Park SS, Thomas PE, Nims RW, Lubet RA. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse Biochem Pharmacol. 1993 Sep 1;46(5):933-43.
4: Pohanka M, Zakova J. A Smartphone Camera Colorimetric Assay of Acetylcholinesterase and Butyrylcholinesterase Activity Sensors (Basel). 2021 Mar 5;21(5):1796.
5: Zhai S, Dai R, Wei X, Friedman FK, Vestal RE. Inhibition of methoxyresorufin demethylase activity by flavonoids in human liver microsomes Life Sci. 1998;63(8):PL119-23.
6: Kim D, Guengerich FP. Enhancement of 7-methoxyresorufin O-demethylation activity of human cytochrome P450 1A2 by molecular breeding Arch Biochem Biophys. 2004 Dec 1;432(1):102-8.
7: Estari RK, Dong J, Chan WK, Park MS, Zhou Z. Time effect of rutaecarpine on caffeine pharmacokinetics in rats Biochem Biophys Rep. 2021 Sep 6;28:101121.
8: Hadjokas NE, Dai R, Friedman FK, Spence MJ, Cusack BJ, Vestal RE, Ma Y. Arginine to lysine 108 substitution in recombinant CYP1A2 abolishes methoxyresorufin metabolism in lymphoblastoid cells Br J Pharmacol. 2002 Jun;136(3):347-52.
9: Roberts EA, Xie ZW, Yang S, Lipa J. Inducibility of enzyme activities associated with the cytochrome P-450 1A family, ethoxyresorufin O-deethylase, and methoxyresorufin O-demethylase in human hepatocyte lines derived from normal liver tissue Drug Metab Dispos. 1993 Jan-Feb;21(1):56-61.
10: Ibor OR, Eni G, Andem AB, Bassey IU, Arong GA, Asor J, Regoli F, Arukwe A. Biotransformation and oxidative stress responses in relation to tissue contaminant burden in Clarias gariepinus exposed to simulated leachate from a solid waste dumpsite in Calabar, Nigeria Chemosphere. 2020 Aug;253:126630.

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