Lithium Acetoacetate (Highly Pure)

Description

Lithium Acetoacetate (Highly Pure)
Catalog number: B2012100
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 g
Molecular Weight or Concentration: 108 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Acetoacetic Acid Lithium Salt, ketone indicator
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Cohen-Harazi R, Hofmann S, Kogan V, Fulman-Levy H, Abaev K, Shovman O, Brider T, Koman I. Cytotoxicity of Exogenous Acetoacetate in Lithium Salt Form Is Mediated by Lithium and Not Acetoacetate Anticancer Res. 2020 Jul;40(7):3831-3837.
2: Vidali S, Aminzadeh-Gohari S, Vatrinet R, Iommarini L, Porcelli AM, Kofler B, Feichtinger RG. Lithium and Not Acetoacetate Influences the Growth of Cells Treated with Lithium Acetoacetate Int J Mol Sci. 2019 Jun 25;20(12):3104.
3: Harada H, Senda D, Shima T, Nakane C. Carboxylesterases for the hydrolysis of acetoacetate esters and their applications in terpenoid production using Escherichia coli Appl Microbiol Biotechnol. 2021 Aug;105(14-15):5821-5832.
4: HALL LM. Preparation of crystalline lithium acetoacetate Anal Biochem. 1962 Jan;3:75-80.
5: Gómez E. Acetoacetate and beta-D-hydroxybutyrate as energy substrates during early bovine embryo development in vitro Theriogenology. 1997 Jul 1;48(1):63-74.
6: Thaler S, Choragiewicz TJ, Rejdak R, Fiedorowicz M, Turski WA, Tulidowicz-Bielak M, Zrenner E, Schuettauf F, Zarnowski T. Neuroprotection by acetoacetate and β-hydroxybutyrate against NMDA-induced RGC damage in rat–possible involvement of kynurenic acid Graefes Arch Clin Exp Ophthalmol. 2010 Dec;248(12):1729-35.
7: Noh HS, Hah YS, Nilufar R, Han J, Bong JH, Kang SS, Cho GJ, Choi WS. Acetoacetate protects neuronal cells from oxidative glutamate toxicity J Neurosci Res. 2006 Mar;83(4):702-9.
8: Harada H, Yu F, Okamoto S, Kuzuyama T, Utsumi R, Misawa N. Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli Appl Microbiol Biotechnol. 2009 Jan;81(5):915-25.
9: Franklin ST, Young JW, Nonnecke BJ. Effects of ketones, acetate, butyrate, and glucose on bovine lymphocyte proliferation J Dairy Sci. 1991 Aug;74(8):2507-14.
10: Sartorelli P, Paltrinieri S, Agnes F. Non-specific immunity and ketone bodies. I: In vitro studies on chemotaxis and phagocytosis in ovine neutrophils Zentralbl Veterinarmed A. 1999 Dec;46(10):613-9.

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