Lawesson Reagent

Product Description

Lawesson Reagent
Catalog number: B2012969
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 5 g
Molecular Weight or Concentration: 404.5 g/mol
Supplied as: Lyophilized Powder
Applications: molecular tool for various biochemical applications
Storage: 2-8°C
Keywords: 2,4-Bis(4-methoxyphenyl)-2,4-dithioxo-1,3,2,4-dithiadiphosphetane, 2,4-Bis-(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide, 4-Methoxyphenylthiophosphoric cyclic di(thioanhydride), LR
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Khatoon H, Abdulmalek E. A Focused Review of Synthetic Applications of Lawesson’s Reagent in Organic Synthesis Molecules. 2021 Nov 17;26(22):6937.
2: Yin G, Wang X, Wang Y, Shi T, Zeng Y, Wang Y, Peng X, Wang Z. Lawesson’s reagent promoted deoxygenation of azlactones for the syntheses of 2,4-disubstituted thiazoles Org Biomol Chem. 2022 Dec 14;20(48):9589-9592.
3: Saeed A, Mehfooz H, Larik FA, Faisal M, Channar PA. Applications of Lawesson’s reagent in the synthesis of naturally occurring steroids and terpenoids J Asian Nat Prod Res. 2017 Nov;19(11):1114-1123.
4: Koval’skaya AV, Petrova PR, Tsypyshev DO, Lobov AN, Tsypysheva IP. Thionation of quinolizidine alkaloids and their derivatives via Lawesson’s reagent Nat Prod Res. 2022 Jul;36(14):3538-3543.
5: Wu K, Ling Y, Ding A, Jin L, Sun N, Hu B, Shen Z, Hu X. A chromatography-free and aqueous waste-free process for thioamide preparation with Lawesson’s reagent Beilstein J Org Chem. 2021 Apr 9;17:805-812.
6: Nicolau LA, Silva RO, Damasceno SR, Carvalho NS, Costa NR, Aragão KS, Barbosa AL, Soares PM, Souza MH, Medeiros JV. The hydrogen sulfide donor, Lawesson’s reagent, prevents alendronate-induced gastric damage in rats Braz J Med Biol Res. 2013 Aug;46(8):708-14.
7: Niijima E, Imai T, Suzuki H, Fujimoto Y, Kitagawa O. Thionation of Optically Pure N-C Axially Chiral Quinazolin-4-one Derivatives with Lawesson’s Reagent J Org Chem. 2021 Jan 1;86(1):709-715.
8: Huang P, Zhang R, Liang Y, Dong D. Lawesson’s reagent-initiated domino reaction of aminopropenoyl cyclopropanes: synthesis of thieno[3,2-c]pyridinones Org Biomol Chem. 2012 Feb 28;10(8):1639-44.
9: Kaleta Z, Makowski BT, Soós T, Dembinski R. Thionation using fluorous Lawesson’s reagent Org Lett. 2006 Apr 13;8(8):1625-8.
10: Giofrè SV, Mancuso R, Araniti F, Romeo R, Iannazzo D, Abenavoli MR, Gabriele B. Microwave-Assisted Synthesis of Sulfurated Heterocycles with Herbicidal Activity: Reaction of 2-Alkynylbenzoic Acids with Lawesson’s Reagent Chempluschem. 2019 Jul;84(7):942-950.

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