L-Pyroglutamyl-L-arginyl-L-threonyl-L-lysyl-L-arginine 4-methylcoumaryl-7-amide

Product Description

L-Pyroglutamyl-L-arginyl-L-threonyl-L-lysyl-L-arginine 4-methylcoumaryl-7-amide
Catalog number: MDP0207
CAS Number: 1009549-31-8
Sequence: L-Pyroglutamyl-L-arginyl-L-threonyl-L-lysyl-L-arginine 4-methylcoumaryl-7-amide
Amount: 1 mg
Molecular Weight: 827.6 g/mol
Supplied as: Powder
Applications: molecular tool for various biochemical applications
Storage: -20 °C
WARNING: For in vitro Research Use Only. NOT for use on humans or animals.
Grade: Biotechnology grade. All products are highly pure.

References:
1: Luo L, Luo JZ, Jackson I. Tripeptide amide L-pyroglutamyl-histidyl-L-prolineamide (L-PHP-thyrotropin-releasing hormone, TRH) promotes insulin-producing cell proliferation Curr Aging Sci. 2013 Feb;6(1):8-13.
2: Kurath P, Thomas AM. N-Carbobenzoxy-L-pyroglutamyl-L-hitidyl peptides Helv Chim Acta. 1973;56(5):1656-61.
3: Filippova IYu, Lysogorskaya EN, Oksenoit ES, Rudenskaya GN, Stepanov VM. L-Pyroglutamyl-L-phenylalanyl-L-leucine-p-nitroanilide–a chromogenic substrate for thiol proteinase assay Anal Biochem. 1984 Dec;143(2):293-7.
4: Fujiwara K, Kitagawa T, Tsuru D. Inactivation of pyroglutamyl aminopeptidase by L-pyroglutamyl chloromethyl ketone Biochim Biophys Acta. 1981 Mar 13;658(1):10-6.
5: Kramps JA, van Twisk C, van der Linden AC. L-Pyroglutamyl-L-prolyl-L-valine-p-nitroanilide, a highly specific substrate for granulocyte elastase Scand J Clin Lab Invest. 1983 Sep;43(5):427-32.
6: Fujiwara K, Matsumoto E, Kitagawa T, Tsuru D. Inactivation of pyroglutamyl aminopeptidase by N alpha-carbobenzoxy-L-pyroglutamyl chloromethyl ketone J Biochem. 1981 Aug;90(2):433-7.
7: Abe K, Watanabe N, Kosaka T, Yamada M, Tokui T, Ikeda T. Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol Biol Pharm Bull. 2003 Nov;26(11):1528-33.
8: Tanaka H, Shimazu T, Sugimoto H, Yoshioka T, Sugimoto T. A sensitive and specific assay for granulocyte elastase in inflammatory tissue fluid using L-pyroglutamyl-L-prolyl-L-valine-p-nitroanilide Clin Chim Acta. 1990 Feb 28;187(2):173-80.
9: Giannola LI, De Caro V, Avellone G, Bousquet E. L-pyroglutamyl-L-tryptophan derivatives as potential drug carriers. II.: Permeation behaviour and stability in the gastro-intestinal tract Pharmazie. 1996 Jul;51(7):487-9.
10: Görbitz CH, Krane J. NMR and molecular dynamics study of the tripeptide L-pyroglutamyl-L-histidylglycine Acta Chem Scand (Cph). 1993 Oct;47(10):979-84.

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