Hydroxy Proline (High Purity Biotechnology Grade)

$150.00

Catalog Number: B2010190 (5 g)
Hydroxy Proline is a high quality research product used as multipurpose amino acid for protein synthesis, reagent stabilization, preparation of culture media and more. Custom bulk orders of this product are available upon request.

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SKU: B2010190 Category:

Description

Hydroxy Proline
Catalog number: B2010190
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 5 g
pH: na
Supplied as: Ready-to-use
Appearance: Powder
Applications: multipurpose amino acid for protein synthesis, reagent stabilization, preparation of culture media and more.
Storage: Room temperature
Keywords: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

References:
1: Watanabe S, Fukumori F, Miyazaki M, Tagami S, Watanabe Y. Characterization of
a Novel cis-3-Hydroxy_l_Proline Dehydratase and a trans-3-Hydroxy-
l-Proline Dehydratase from Bacteria. J Bacteriol. 2017 Jul 25;199(16):e00255-17.

2: Yang H, Male M, Li Y, Wang N, Zhao C, Jin S, Hu J, Chen Z, Ye Z, Xu H.
Efficacy of Hydroxy_L_proline (HYP) analogs in the treatment of primary
hyperoxaluria in Drosophila Melanogaster. BMC Nephrol. 2018 Jul 6;19(1):167.

3: Zhang HL, Zhang C, Pei CH, Han MN, Xu ZD, Li CH, Li W. Efficient production
of trans-4-Hydroxy-l-proline from glucose by metabolic engineering of
recombinant Escherichia coli. Lett Appl Microbiol. 2018 May;66(5):400-408.

4: Prejanò M , Romeo I , Sgrizzi L , Russo N , Marino T . Why hydroxy-proline
improves the catalytic power of the peptidoglycan N-deacetylase enzyme: insight
from theory. Phys Chem Chem Phys. 2019 Nov 14;21(42):23338-23345.

5: Lawrence YA, Rodrigues-Hoffmann A, Steiner JM, Suchodolski JS, Shankar S,
Klemashevich CL, Lidbury JA. Development, validation, and application of a
liquid chromatography-tandem mass spectrometry method for quantitative
determination of trans-4-hydroxy-l-proline concentration in the serum of dogs
with chronic hepatitis. Am J Vet Res. 2019 May;80(5):434-440.

6: Wang XC, Liu J, Zhao J, Ni XM, Zheng P, Guo X, Sun CM, Sun JB, Ma YH.
Efficient production of trans-4-hydroxy-l-proline from glucose using a new
trans-proline 4-hydroxylase in Escherichia coli. J Biosci Bioeng. 2018
Oct;126(4):470-477.

7: Ferraris DM, Miggiano R, Watanabe S, Rizzi M. Structure of Thermococcus
litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-
complexed form. Biochem Biophys Res Commun. 2019 Aug 13;516(1):189-195.

8: Watanabe S, Tajima K, Fujii S, Fukumori F, Hara R, Fukuda R, Miyazaki M, Kino
K, Watanabe Y. Functional characterization of aconitase X as a cis-3-hydroxy-L-
proline dehydratase. Sci Rep. 2016 Dec 8;6:38720.

9: Zhang X, Kumar R, Vetting MW, Zhao S, Jacobson MP, Almo SC, Gerlt JA. A
unique cis-3-hydroxy_l_proline dehydratase in the enolase superfamily. J Am Chem
Soc. 2015 Feb 4;137(4):1388-91.

10: Hanson RL, Johnston RM, Goldberg SL, Parker WL, Patel RN. Enzymatic
preparation of 5-hydroxy_L_proline, N-Cbz-5-hydroxy-L-proline, and
N-Boc-5-hydroxy-L-proline from (α-N-protected)-L-ornithine using a transaminase
or an amine oxidase. Enzyme Microb Technol. 2011 May 6;48(6-7):445-53.

11: Chen K, Pang Y, Zhang B, Feng J, Xu S, Wang X, Ouyang P. Process
optimization for enhancing production of cis-4-hydroxy-L-proline by engineered
Escherichia coli. Microb Cell Fact. 2017 Nov 22;16(1):210.

Products Related to Hydroxy Proline : Biochemical Buffers and Solutions

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