Hydroxy Proline (High Purity Biotechnology Grade)
Catalog Number: B2010190 (5 g)
Hydroxy Proline is a high quality research product used as multipurpose amino acid for protein synthesis, reagent stabilization, preparation of culture media and more. Custom bulk orders of this product are available upon request.
Catalog number: B2010190
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 5 g
Supplied as: Ready-to-use
Applications: multipurpose amino acid for protein synthesis, reagent stabilization, preparation of culture media and more.
Storage: Room temperature
Keywords: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.
1: Watanabe S, Fukumori F, Miyazaki M, Tagami S, Watanabe Y. Characterization of
a Novel cis-3-Hydroxy_l_Proline Dehydratase and a trans-3-Hydroxy-
l-Proline Dehydratase from Bacteria. J Bacteriol. 2017 Jul 25;199(16):e00255-17.
2: Yang H, Male M, Li Y, Wang N, Zhao C, Jin S, Hu J, Chen Z, Ye Z, Xu H.
Efficacy of Hydroxy_L_proline (HYP) analogs in the treatment of primary
hyperoxaluria in Drosophila Melanogaster. BMC Nephrol. 2018 Jul 6;19(1):167.
3: Zhang HL, Zhang C, Pei CH, Han MN, Xu ZD, Li CH, Li W. Efficient production
of trans-4-Hydroxy-l-proline from glucose by metabolic engineering of
recombinant Escherichia coli. Lett Appl Microbiol. 2018 May;66(5):400-408.
4: Prejanò M , Romeo I , Sgrizzi L , Russo N , Marino T . Why hydroxy-proline
improves the catalytic power of the peptidoglycan N-deacetylase enzyme: insight
from theory. Phys Chem Chem Phys. 2019 Nov 14;21(42):23338-23345.
5: Lawrence YA, Rodrigues-Hoffmann A, Steiner JM, Suchodolski JS, Shankar S,
Klemashevich CL, Lidbury JA. Development, validation, and application of a
liquid chromatography-tandem mass spectrometry method for quantitative
determination of trans-4-hydroxy-l-proline concentration in the serum of dogs
with chronic hepatitis. Am J Vet Res. 2019 May;80(5):434-440.
6: Wang XC, Liu J, Zhao J, Ni XM, Zheng P, Guo X, Sun CM, Sun JB, Ma YH.
Efficient production of trans-4-hydroxy-l-proline from glucose using a new
trans-proline 4-hydroxylase in Escherichia coli. J Biosci Bioeng. 2018
7: Ferraris DM, Miggiano R, Watanabe S, Rizzi M. Structure of Thermococcus
litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-
complexed form. Biochem Biophys Res Commun. 2019 Aug 13;516(1):189-195.
8: Watanabe S, Tajima K, Fujii S, Fukumori F, Hara R, Fukuda R, Miyazaki M, Kino
K, Watanabe Y. Functional characterization of aconitase X as a cis-3-hydroxy-L-
proline dehydratase. Sci Rep. 2016 Dec 8;6:38720.
9: Zhang X, Kumar R, Vetting MW, Zhao S, Jacobson MP, Almo SC, Gerlt JA. A
unique cis-3-hydroxy_l_proline dehydratase in the enolase superfamily. J Am Chem
Soc. 2015 Feb 4;137(4):1388-91.
10: Hanson RL, Johnston RM, Goldberg SL, Parker WL, Patel RN. Enzymatic
preparation of 5-hydroxy_L_proline, N-Cbz-5-hydroxy-L-proline, and
N-Boc-5-hydroxy-L-proline from (α-N-protected)-L-ornithine using a transaminase
or an amine oxidase. Enzyme Microb Technol. 2011 May 6;48(6-7):445-53.
11: Chen K, Pang Y, Zhang B, Feng J, Xu S, Wang X, Ouyang P. Process
optimization for enhancing production of cis-4-hydroxy-L-proline by engineered
Escherichia coli. Microb Cell Fact. 2017 Nov 22;16(1):210.
Products Related to Hydroxy Proline : Biochemical Buffers and Solutions
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