Human Cxcl12 Protein

Description

Human Cxcl12 Protein
Catalog number: B2012084
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 µg
Molecular Weight or Concentration: 250 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: Pbsf protein, Scyb12 protein, Sdf1 protein, Tlsf protein, Tpar1 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Teicher BA, Fricker SP. CXCL12 (SDF-1)/CXCR4 pathway in cancer Clin Cancer Res. 2010 Jun 1;16(11):2927-31.
2: Zhou W, Guo S, Liu M, Burow ME, Wang G. Targeting CXCL12/CXCR4 Axis in Tumor Immunotherapy Curr Med Chem. 2019;26(17):3026-3041.
3: Daniel SK, Seo YD, Pillarisetty VG. The CXCL12-CXCR4/CXCR7 axis as a mechanism of immune resistance in gastrointestinal malignancies Semin Cancer Biol. 2020 Oct;65:176-188.
4: Janssens R, Struyf S, Proost P. The unique structural and functional features of CXCL12 Cell Mol Immunol. 2018 Apr;15(4):299-311.
5: Mousavi A. CXCL12/CXCR4 signal transduction in diseases and its molecular approaches in targeted-therapy Immunol Lett. 2020 Jan;217:91-115.
6: Khare T, Bissonnette M, Khare S. CXCL12-CXCR4/CXCR7 Axis in Colorectal Cancer: Therapeutic Target in Preclinical and Clinical Studies Int J Mol Sci. 2021 Jul 9;22(14):7371.
7: Lu J, Wang Z, Ren L, Sun Y, Cao Y, Xiong Y, Zhang Y. Expression and Functional Analysis of CXCL12 and Its Receptors in Human Term Trophoblast Cells Reprod Sci. 2020 Jan;27(1):46-54.
8: Luo N, Chen DD, Liu L, Li L, Cheng ZP. CXCL12 promotes human ovarian cancer cell invasion through suppressing ARHGAP10 expression Biochem Biophys Res Commun. 2019 Oct 20;518(3):416-422.
9: Yamada T, Hasegawa S, Hasebe Y, Kawagishi-Hotta M, Arima M, Iwata Y, Kobayashi T, Numata S, Yamamoto N, Nakata S, Sugiura K, Akamatsu H. CXCL12 regulates differentiation of human immature melanocyte precursors as well as their migration Arch Dermatol Res. 2019 Jan;311(1):55-62.
10: Potter ML, Smith K, Vyavahare S, Kumar S, Periyasamy-Thandavan S, Hamrick M, Isales CM, Hill WD, Fulzele S. Characterization of Differentially Expressed miRNAs by CXCL12/SDF-1 in Human Bone Marrow Stromal Cells Biomol Concepts. 2021 Oct 13;12(1):132-143.

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