Human CRYBA4 Protein


Catalog Number: B2012035 (100 µg)
Human CRYBA4 Protein is a high quality recombinant human CRYBA4 protein His tagged and expressed in E.coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human CRYBA4 Protein
Catalog number: B2012035
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 1.0 mg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: CRYBA 4, CRYBA4, CRYBA-4, CRYBA 4 protein, Beta-crystallin A4 protein, MCOPCT4 protein, CRYBA-4 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Billingsley G, Santhiya ST, Paterson AD, Ogata K, Wodak S, Hosseini SM, Manisastry SM, Vijayalakshmi P, Gopinath PM, Graw J, Héon E. CRYBA4, a novel human cataract gene, is also involved in microphthalmia Am J Hum Genet. 2006 Oct;79(4):702-9.
2: Li W, Ji Q, Wei Z, Chen YL, Zhang Z, Yin X, Aghmiuni SK, Liu M, Chen W, Shi L, Chen Q, Du X, Yu L, Cao MJ, Wang Z, Huang S, Jin T, Wang Q. Biochemical characterization of G64W mutant of acidic beta-crystallin 4 Exp Eye Res. 2019 Sep;186:107712.
3: Wang Z, Huang C, Lv H, Zhang M, Li X. In silico analysis and high-risk pathogenic phenotype predictions of non-synonymous single nucleotide polymorphisms in human Crystallin beta A4 gene associated with congenital cataract PLoS One. 2020 Jan 14;15(1):e0227859.
4: Hayashi N, Sato T, Kokabu S, Usui M, Yumoto M, Ikami E, Sakamoto Y, Nifuji A, Hayata T, Noda M, Yoda T. Possible association of oestrogen and Cryba4 with masticatory muscle tendon-aponeurosis hyperplasia Oral Dis. 2019 Jan;25(1):274-281.
5: Zhou G, Zhou N, Hu S, Zhao L, Zhang C, Qi Y. A missense mutation in CRYBA4 associated with congenital cataract and microcornea Mol Vis. 2010 Jun 5;16:1019-24.
6: Limi S, Zhao Y, Guo P, Lopez-Jones M, Zheng D, Singer RH, Skoultchi AI, Cvekl A. Bidirectional Analysis of Cryba4-Crybb1 Nascent Transcription and Nuclear Accumulation of Crybb3 mRNAs in Lens Fibers Invest Ophthalmol Vis Sci. 2019 Jan 2;60(1):234-244.
7: van Rens GL, Geurts van Kessel AH, Bloemendal H. Localization of the beta A4-crystallin gene (CRYBA4) on human chromosome 22 in the region q11.2–>q13.1 Cytogenet Cell Genet. 1992;61(3):180-3.
8: Weatherbee BAT, Barton JR, Siddam AD, Anand D, Lachke SA. Molecular characterization of the human lens epithelium-derived cell line SRA01/04 Exp Eye Res. 2019 Nov;188:107787.
9: Bijlsma EK, Hulsebos TJ. A PstI polymorphism associated with CRYBA4 on human chromosome 22 Hum Mol Genet. 1993 Nov;2(11):1984.
10: Siggs OM, Javadiyan S, Sharma S, Souzeau E, Lower KM, Taranath DA, Black J, Pater J, Willoughby JG, Burdon KP, Craig JE. Partial duplication of the CRYBB1-CRYBA4 locus is associated with autosomal dominant congenital cataract Eur J Hum Genet. 2017 Jun;25(6):711-718.

Products Related to Human CRYBA4 Protein can be found at Proteins

Additional information

Weight 48 oz
Dimensions 8 × 8 × 8 in

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