Human CLEC4E Protein

Product Description

Human CLEC4E Protein
Catalog number: B2011971
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 µg
Molecular Weight or Concentration: 250 µg/mL
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20 °C
Keywords: C-type lectin domain family 4 protein, member E protein, MINCLE protein, CLECSF9 protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Veltman D, Wu M, Pokreisz P, Claus P, Gillijns H, Caluwé E, Vanhaverbeke M, Gsell W, Himmelreich U, Sinnaeve PR, Janssens SP. Clec4e-Receptor Signaling in Myocardial Repair After Ischemia-Reperfusion Injury JACC Basic Transl Sci. 2021 Aug 23;6(8):631-646.
2: Clément M, Basatemur G, Masters L, Baker L, Bruneval P, Iwawaki T, Kneilling M, Yamasaki S, Goodall J, Mallat Z. Necrotic Cell Sensor Clec4e Promotes a Proatherogenic Macrophage Phenotype Through Activation of the Unfolded Protein Response Circulation. 2016 Oct 4;134(14):1039-1051.
3: Olvany JM, Sausville LN, White MJ, Tacconelli A, Tavera G, Sobota RS, Ciccacci C, Bohlbro AS, Wejse C, Williams SM, Sirugo G. CLEC4E (Mincle) genetic variation associates with pulmonary tuberculosis in Guinea-Bissau (West Africa) Infect Genet Evol. 2020 Nov;85:104560.
4: Zhou W, Wu L, Song J, Jiao L, Zhou Y, Zhou J, Wang N, Liu T, Zhao Z, Bai H, Wu T, Ying B. A case-control study on correlation between the single nucleotide polymorphism of CLEC4E and the susceptibility to tuberculosis among Han people in Western China BMC Infect Dis. 2021 Aug 10;21(1):788.
5: Miyake Y, Yamasaki S. Immune Recognition of Pathogen-Derived Glycolipids Through Mincle Adv Exp Med Biol. 2020;1204:31-56.
6: Thiyagarajan D, Fismen S, Seredkina N, Jacobsen S, Elung-Jensen T, Kamper AL, Fenton CG, Rekvig OP, Mortensen ES. Silencing of renal DNaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e PLoS One. 2012;7(3):e34080.
7: Kabuye D, Chu Y, Lao W, Jin G, Kang H. Association between CLEC4E gene polymorphism of mincle and pulmonary tuberculosis infection in a northern Chinese population Gene. 2019 Aug 20;710:24-29.
8: Lu X, Nagata M, Yamasaki S. Mincle: 20 years of a versatile sensor of insults Int Immunol. 2018 May 24;30(6):233-239.
9: Logie C, van Schaik T, Pompe T, Pietsch K. Fibronectin-functionalization of 3D collagen networks supports immune tolerance and inflammation suppression in human monocyte-derived macrophages Biomaterials. 2021 Jan;268:120498.
10: Bowker N, Salie M, Schurz H, van Helden PD, Kinnear CJ, Hoal EG, Möller M. Polymorphisms in the Pattern Recognition Receptor Mincle Gene (CLEC4E) and Association with Tuberculosis Lung. 2016 Oct;194(5):763-7.

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