Human Calcitonin Gene-Related Peptide-I

Description

Human Calcitonin Gene-Related Peptide-I
Catalog number: B2014712
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 1 mg
Molecular Weight or Concentration: 3789.31 g/mol
Supplied as: Solid
Applications: molecular tool for various biochemical applications
Storage: −20°C
Keywords: CalCalcitonin Gene-Related Peptide-I, CGRP-I, αCGRP
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Russell FA, King R, Smillie SJ, Kodji X, Brain SD. Calcitonin gene-related peptide: physiology and pathophysiology Physiol Rev. 2014 Oct;94(4):1099-142.
2: Russo AF. Calcitonin gene-related peptide (CGRP): a new target for migraine Annu Rev Pharmacol Toxicol. 2015;55:533-52.
3: Russo AF, Hay DL. CGRP physiology, pharmacology, and therapeutic targets: migraine and beyond Physiol Rev. 2023 Apr 1;103(2):1565-1644.
4: Singh Y, Gupta G, Shrivastava B, Dahiya R, Tiwari J, Ashwathanarayana M, Sharma RK, Agrawal M, Mishra A, Dua K. Calcitonin gene-related peptide (CGRP): A novel target for Alzheimer’s disease CNS Neurosci Ther. 2017 Jun;23(6):457-461.
5: Zhu J, Pedersen MD, Ahmed LS, Abdolalizadeh B, Grell AS, Berg JO, Thulstrup PW, Franzyk H, Edvinsson L, Sams A, Sheykhzade M, Hansen PR. Fluorescent Analogues of Human α-Calcitonin Gene-Related Peptide with Potent Vasodilator Activity Int J Mol Sci. 2020 Feb 17;21(4):1343.
6: Edvinsson L, Haanes KA, Warfvinge K, Krause DN. CGRP as the target of new migraine therapies – successful translation from bench to clinic Nat Rev Neurol. 2018 Jun;14(6):338-350.
7: Ashina H, Newman L, Ashina S. Calcitonin gene-related peptide antagonism and cluster headache: an emerging new treatment Neurol Sci. 2017 Dec;38(12):2089-2093.
8: O’Halloran DJ, Bloom SR. Calcitonin gene related peptide BMJ. 1991 Mar 30;302(6779):739-40.
9: Preibisz JJ. Calcitonin gene-related peptide and regulation of human cardiovascular homeostasis Am J Hypertens. 1993 May;6(5 Pt 1):434-50.
10: Rubio-Beltran E, Chan KY, Danser AJ, MaassenVanDenBrink A, Edvinsson L. Characterisation of the calcitonin gene-related peptide receptor antagonists ubrogepant and atogepant in human isolated coronary, cerebral and middle meningeal arteries Cephalalgia. 2020 Apr;40(4):357-366.

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