Human Aldolase-A


Catalog Number: B2012368 (20 ug)
Human Aldolase-A is a high quality recombinant human Aldolase-A produced in E. coli. This product has been used as molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request.

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Human Aldolase-A
Catalog number: B2012368
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 20 ug
Molecular Weight or Concentration: 41.5 kDa
Supplied as: Solution
Applications: molecular tool for various biochemical applications
Storage: -20°C
Keywords: Fructose-bisphosphate aldolase A, Muscle-type aldolase, Lung cancer antigen NY-LU-1, ALDOA, ALDA
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

1: Ali M, Rellos P, Cox TM. Hereditary fructose intolerance J Med Genet. 1998 May;35(5):353-65.
2: Qin W, Qin K, Zhang Y, Jia W, Chen Y, Cheng B, Peng L, Chen N, Liu Y, Zhou W, Wang YL, Chen X, Wang C. S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate Nat Chem Biol. 2019 Oct;15(10):983-991.
3: Li X, Yu C, Luo Y, Lin J, Wang F, Sun X, Gao Y, Tan W, Xia Q, Kong X. Aldolase A Enhances Intrahepatic Cholangiocarcinoma Proliferation and Invasion through Promoting Glycolysis Int J Biol Sci. 2021 Apr 23;17(7):1782-1794.
4: Fenton KD, Meneely KM, Wu T, Martin TA, Swint-Kruse L, Fenton AW, Lamb AL. Substitutions at a rheostat position in human aldolase A cause a shift in the conformational population Protein Sci. 2022 Feb;31(2):357-370.
5: Takasaki Y, Takahashi I, Mukai T, Hori K. Human aldolase A of a hemolytic anemia patient with Asp-128—-Gly substitution: characteristics of an enzyme generated in E. coli transfected with the expression plasmid pHAAD128G J Biochem. 1990 Aug;108(2):153-7.
6: Lu J, Suzuki T, Satoh M, Chen S, Tomonaga T, Nomura F, Suzuki N. Involvement of aldolase A in X-ray resistance of human HeLa and UV(r)-1 cells Biochem Biophys Res Commun. 2008 May 9;369(3):948-52.
7: Izzo P, Costanzo P, Lupo A, Rippa E, Paolella G, Salvatore F. Human aldolase A gene. Structural organization and tissue-specific expression by multiple promoters and alternate mRNA processing Eur J Biochem. 1988 Jul 1;174(4):569-78.
8: Izzo P, Costanzo P, Lupo A, Rippa E, Borghese AM, Paolella G, Salvatore F. A new human species of aldolase A mRNA from fibroblasts Eur J Biochem. 1987 Apr 1;164(1):9-13.
9: Kishi H, Mukai T, Hirono A, Fujii H, Miwa S, Hori K. Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation Proc Natl Acad Sci U S A. 1987 Dec;84(23):8623-7.
10: Asaka M, Miyazaki T, Hollinger FB, Alpert E. Human aldolase B serum levels: a marker of liver injury Hepatology. 1984 May-Jun;4(3):531-5.

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