Human 14.3.3 Eta Protein

Product Description

Human 14.3.3 Eta Protein
Catalog number: B2011051
Lot number: Batch Dependent
Expiration Date: Batch dependent
Amount: 100 μg
Source: Recombinant (E. coli)
Molecular Weight or Concentration: 55 kDa (including GST Tag)
Supplied as: Lyophilized
Applications: molecular tool for various chemical, biochemical and immunological applications
Storage: -20°C
Keywords: tyrosine 3/tryptophan 5 monooxygenase activation protein eta polypeptide protein, Protein AS1 protein, YWHAH protein, 14.3.3 eta, YWHA 1., HGNC:12853 protein, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein
Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um.

References:
1: Stevers LM, Sijbesma E, Botta M, MacKintosh C, Obsil T, Landrieu I, Cau Y, Wilson AJ, Karawajczyk A, Eickhoff J, Davis J, Hann M, O’Mahony G, Doveston RG, Brunsveld L, Ottmann C. Modulators of 14-3-3 Protein-Protein Interactions J Med Chem. 2018 May 10;61(9):3755-3778.
2: Wang D, Cui Y, Lei H, Cao D, Tang G, Huang H, Yuan T, Rao L, Mo B. Diagnostic accuracy of 14-3-3 η protein in rheumatoid arthritis: A meta-analysis Int J Rheum Dis. 2020 Nov;23(11):1443-1451.
3: Gogl G, Tugaeva KV, Eberling P, Kostmann C, Trave G, Sluchanko NN. Hierarchized phosphotarget binding by the seven human 14-3-3 isoforms Nat Commun. 2021 Mar 15;12(1):1677.
4: Fu W, Hu W, Yi YS, Hettinghouse A, Sun G, Bi Y, He W, Zhang L, Gao G, Liu J, Toyo-Oka K, Xiao G, Solit DB, Loke P, Liu CJ. TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity J Clin Invest. 2021 Aug 16;131(16):e144016.
5: Lentini Santo D, Petrvalska O, Obsilova V, Ottmann C, Obsil T. Stabilization of Protein-Protein Interactions between CaMKK2 and 14-3-3 by Fusicoccins ACS Chem Biol. 2020 Nov 20;15(11):3060-3071.
6: Park E, Rawson S, Li K, Kim BW, Ficarro SB, Pino GG, Sharif H, Marto JA, Jeon H, Eck MJ. Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes Nature. 2019 Nov;575(7783):545-550.
7: Kalabova D, Filandr F, Alblova M, Petrvalska O, Horvath M, Man P, Obsil T, Obsilova V. 14-3-3 protein binding blocks the dimerization interface of caspase-2 FEBS J. 2020 Aug;287(16):3494-3510.
8: Liu Q, Ye Y, Lin X, Yang Y, Wu K, Yu M. Expression of 14-3-3 Zeta Protein in Dexamethasone-Treated Mice and Human TM-1 Cells Curr Eye Res. 2017 Aug;42(8):1124-1129.
9: Lalle M, Fiorillo A. The protein 14-3-3: A functionally versatile molecule in Giardia duodenalis Adv Parasitol. 2019;106:51-103.
10: Guillory X, Hadrović I, de Vink PJ, Sowislok A, Brunsveld L, Schrader T, Ottmann C. Supramolecular Enhancement of a Natural 14-3-3 Protein Ligand J Am Chem Soc. 2021 Sep 1;143(34):13495-13500.

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