Heparin (Lithium) for Interference Testing

$195.00

Catalog Number: B2010201 (1000 U at > 150 U/mg)
Heparin for Interference Testing is a high quality research product used as highly pure Lithium Heparin (>150 U/mg) that can be spiked in specimen to test Lithium Heparin interference in various assays. Custom bulk orders of this product are available upon request.

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SKU: B2010201 Categories: , ,

Description

Heparin for Interference Testing
Catalog number: B2010201
Lot number: Batch Dependent
Expiration Date: Batch dependent
Volume/Weight: 1000 U at > 150 U/mg
pH: na
Supplied as: Ready-to-use
Appearance: Solution
Applications: highly pure Lithium Heparin (>150 U/mg) that can be spiked in specimen to test Lithium Heparin interference in various assays.
Storage: -20C
Keywords: Heparin lithium salt, Li-heparin
Grade: Biotechnology grade. All components are highly pure (minimum 99%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered on a 0.22 um.

All Interference Products Brochure

Interference Testing Brochure

References:
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substitution with animal-component free material. Appl Microbiol Biotechnol.
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2: Cassinelli G, Naggi A. Old and new applications of non-anticoagulant heparin.
Int J Cardiol. 2016 Jun;212 Suppl 1:S14-21.

3: Liu X, St Ange K, Wang X, Lin L, Zhang F, Chi L, Linhardt RJ. Parent heparin
and daughter LMW heparin correlation analysis using LC-MS and NMR. Anal Chim
Acta. 2017 Apr 8;961:91-99.

4: Tyrrell DJ, Horne AP, Holme KR, Preuss JM, Page CP. Heparin in inflammation:
potential therapeutic applications beyond anticoagulation. Adv Pharmacol.
1999;46:151-208.

5: Masuko S, Linhardt RJ. Chemoenzymatic synthesis of the next generation of
ultralow MW heparin therapeutics. Future Med Chem. 2012 Mar;4(3):289-96.

6: Bertini S, Fareed J, Madaschi L, Risi G, Torri G, Naggi A. Characterization
of PF4-Heparin Complexes by Photon Correlation Spectroscopy and Zeta Potential.
Clin Appl Thromb Hemost. 2017 Oct;23(7):725-734.

7: Walenga JM, Lyman GH. Evolution of heparin anticoagulants to ultra-low-
molecular-weight heparins: a review of pharmacologic and clinical differences
and applications in patients with cancer. Crit Rev Oncol Hematol. 2013
Oct;88(1):1-18.

8: Bick RL, Frenkel EP, Walenga J, Fareed J, Hoppensteadt DA. Unfractionated
heparin, low molecular weight heparins, and pentasaccharide: basic mechanism of
actions, pharmacology, and clinical use. Hematol Oncol Clin North Am. 2005
Feb;19(1):1-51, v.

9: Ouyang Y, Zeng Y, Yi L, Tang H, Li D, Linhardt RJ, Zhang Z. Qualitative and
quantitative analysis of heparin and low molecular weight heparins using size
exclusion chromatography with multiple angle laser scattering/refractive index
and inductively coupled plasma/mass spectrometry detectors. J Chromatogr A. 2017
Nov 3;1522:56-61.

10: Hull RD, Pineo GF, Stein P. Heparin and low-molecular-weight heparin therapy
for venous thromboembolism. The twilight of anticoagulant monitoring. Int
Angiol. 1998 Dec;17(4):213-24.

11: Xiao Z, Tappen BR, Ly M, Zhao W, Canova LP, Guan H, Linhardt RJ. Heparin
mapping using heparin lyases and the generation of a novel low molecular weight
heparin. J Med Chem. 2011 Jan 27;54(2):603-10.

12: Padma V, Fisher M, Moonis M. Role of heparin and low-molecular-weight
heparins in the management of acute ischemic stroke. Expert Rev Cardiovasc Ther.
2006 May;4(3):405-15.

13: Li G, Yang B, Li L, Zhang F, Xue C, Linhardt RJ. Analysis of 3-O-sulfo
group-containing heparin tetrasaccharides in heparin by liquid chromatography-
mass spectrometry. Anal Biochem. 2014 Jun 15;455:3-9.

14: Kalathottukaren MT, Abbina S, Yu K, Shenoi RA, Creagh AL, Haynes C,
Kizhakkedathu JN. A Polymer Therapeutic Having Universal Heparin Reversal
Activity: Molecular Design and Functional Mechanism. Biomacromolecules. 2017 Oct
9;18(10):3343-3358.

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