Gottingen Minipig CSF

Product Description

Gottingen Minipig CSF (1 mL)
Catalog number: B2026749
Lot number: Batch Dependent
Expiration Date: Batch dependent
Molecular Weight or Concentration: NA
Storage: −20°C
Keywords: Gottingen Minipig CSF (1 mL)

References:
– Bergadano, A., Amen, E. M., Jacobsen, B., Belli, S., Vandjour, A., Rapp, C., & Senn, C. (2019). A minimally-invasive serial cerebrospinal fluid sampling model in conscious Gottingen minipigs. Journal of Biological Methods, 6(1), 1.
– Caruso, A., Alvarez-Sanchez, R., Hillebrecht, A., Poirier, A., Schuler, F., Lave, T., et al. (2013). PK/PD assessment in CNS drug discovery: Prediction of CSF concentration in rodents for P-glycoprotein substrates and application to in vivo potency estimation. Biochem Pharmacol, 85(11), 1684-99.
– Di Terlizzi, R., & Platt, S. R. (2009). The function, composition and analysis of cerebrospinal fluid in companion animals: part II – analysis. Vet J, 180(1), 15-32.
– Douville, J., & Emond, F. (2025). Cerebrospinal fluid (CSF) collection from the lumbar site. Gottingen Minipigs Magazine, 69, 4.
– Friden, M., et al. (2009). Knowledge of brain penetration of drugs in minipigs. Cited in Gottingen Minipigs Magazine, 69, 2025.
– Ito, K., & Houston, J. B. (2004). Comparison of minipig, dog, monkey and human drug metabolism and disposition. Cited in Gottingen Minipigs Magazine, 69, 2025.
– Langthaler, K. (2025). This study evaluates the Gottingen minipig as a pharmacokinetic (PK) model for central nervous system (CNS) Research & Development (R&D). Gottingen Minipigs Magazine, 69, 2.
– Obach, R. S. (1999). Prediction of CL from in vitro metabolic stability data. Cited in Gottingen Minipigs Magazine, 69, 2025.
– Shen, D. D., Artru, A. A., & Adkison, K. K. (2004). Principles and applicability of CSF sampling for the assessment of CNS drug delivery and pharmacodynamics. Adv Drug Deliv Rev, 56(12), 1825-57.
– Summerfield, S. G., et al. (2016). Animal PK models and human data. Cited in Gottingen Minipigs Magazine, 69, 2025.
Gottingen Minipig CSF (1 mL)

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